Results 161 to 170 of about 87,161 (272)

Transcriptional regulator NtrC modulates nitrogen assimilation, virulence, and the extracellular glutamine synthetase activity in Acinetobacter baumannii. [PDF]

PLoS One
Alahmar AJ, Elhosseiny NM, Mahmoud RR, Attia AS.   +3 more
europepmc   +1 more source

Glutamine synthetase and GlnR regulate nitrogen metabolism in <i>Paenibacillus polymyxa</i> WLY78. [PDF]

Appl Environ Microbiol, 2023
Zhao X, Song Y, Wang T, Hua C, Hu R, Shang Y, Shi H, Chen S.   +7 more
europepmc   +1 more source

Aminoacyl‐tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (aaRS) are essential enzymes that charge tRNAs with their corresponding amino acids, playing a critical role in protein synthesis. All 37 nuclear‐encoded ARS genes, comprising both cytosolic (ARS1) and mitochondrial (ARS2) isoforms, have now been linked to human disease.
M. I. Mendes, D. E. Smith, V. Spek, A. M. Bosch, W. E. Corpeleijn, M. Engelen, S. A. Fuchs, A. Hadchouel, I. U. Heinemann, R. H. Houtkooper, E. M. M. Hoytema van Konijnenburg, S. Kemp, M. Langeveld, C. D. M. Karnebeek, A. Pop, V. M. Siu, N. I. Wolf, G. S. Salomons   +17 more
wiley   +1 more source

Sequential, chromosome-specific glutamine synthetase double knockout with Cas-CLOVER establishes enhanced CHO platforms for cell line development. [PDF]

Biotechnol Prog
Limia CG, Steffey V, Cheng HC, Machado D, Hart T, McHargue MC, Brizzee C, Crawford J.   +7 more
europepmc   +1 more source

The Role of Glutamine Synthetase (GS) and Glutamate Synthase (GOGAT) in the Improvement of Nitrogen Use Efficiency in Cereals. [PDF]

Biomolecules, 2023
Fortunato S, Nigro D, Lasorella C, Marcotuli I, Gadaleta A, de Pinto MC.   +5 more
europepmc   +1 more source

Spatiotemporal Transcriptomics Characterizes Immune Microenvironment During Mouse Liver Aging

Aging Cell, Volume 25, Issue 5, May 2026.
T cells are the most dynamically altered immune population in the aged liver. Accumulation of CD8+ Tex in aged livers. Spatial enrichment of CD8+ Tex in the portal vein zone. PP hepatocytes promote T cell exhaustion via Lpin1. T cell exhaustion correlates with liver disease progression.
Jiahua Lu, Yuqian Wang, Wenxue Zhao, Zihao Zhao, Zhaoya Gao, Jin Gu, Cheng Li, Jie Cheng   +7 more
wiley   +1 more source

Glutamine synthetase deficiency enhances CD8 T cell survival and stress resilience in the tumor microenvironment. [PDF]

J Immunol
Fisher-Gupta EL, Hathaway ES, Perera JM, Jennings EQ, Chi C, Sewell AE, Stone SH, Muka JE, Sinard RC, DeCorte JA, Chen H, Wilson JT, Meiler J, Rathmell JC.   +13 more
europepmc   +1 more source

Skeletal muscle metabolism in hypokinetic rats [PDF]

Muscle growth, protein metabolism, and amino acid metabolism were studied in various groups of rats. Certain groups were adrenaliectomized; some rats were suspended while others (the controls) were weight bearing. Results show that: (1) metabolic changes
Tischler, M. E.
core   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, Volume 59, Issue 5, May 2026.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

Characterization of glutamine synthetase involved in the fecundity of Rhopalosiphum padi. [PDF]

Sci Rep
Li XY, Wang JQ, Zheng KW, Li YT.
europepmc   +1 more source