Results 151 to 160 of about 87,161 (272)

Validating the role of glutamine synthetase GLN2 during photorespiration in Arabidopsis thaliana. [PDF]

Plant Physiol, 2023
Kobercová E, Melo P, Fischer L.
europepmc   +1 more source

Responses of skeletal muscle to unloading, a review [PDF]

Suspension models were used to study muscle response to reduced activity. During 6 days of tail casting, the soleus (SOL) atrophies while the extensor digitorum longus grows relatively normally.
Henriksen, E. J., Jacob, S., Jaspers, S. R., Tischler, M. E.   +3 more
core   +1 more source

Phylogenetic history shapes the composition of floral scents in a specialized pollination mutualism

New Phytologist, Volume 250, Issue 5, Page 3428-3443, June 2026.
Summary Most studies of the chemical ecology of plant–pollinator interactions emphasize the role of pollinator‐mediated selection in shaping floral scent composition. Nevertheless, phylogeny may constrain the metabolic pathways underlying these profiles, thereby influencing the evolutionary trajectory of the emitted signals.
Li Cao, Nina Joffard, Simon T. Segar, Daniel Souto‐Vilarós, Steven D. Johnson, Bruno Buatois, Anne‐Geneviève Bagnères, Martine Hossaert‐McKey, Magali Proffit   +8 more
wiley   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Control of glnA (glutamine synthetase) expression by urea in non-pathogenic and uropathogenic Escherichia coli. [PDF]

J Bacteriol, 2023
Urs K, Zimmern PE, Reitzer L.
europepmc   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Functional Differences of Glutamine Synthetase Isoenzymes in Wheat Canopy Ammonia Exchange. [PDF]

Int J Mol Sci
Zhang X, Chen J, Song W, Ahmad S, Zhang Z, Li H, Ma X, Wang X, Wei Y.   +8 more
europepmc   +1 more source

A Novel Multimodal LC–MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Stine Christ, Julia Rossmann, Sylvia Richter, Sven Garbade, Glynis Klinke, Nenad Blau, Georg Friedrich Hoffmann, Jürgen Günther Okun, Thomas Opladen   +8 more
wiley   +1 more source