Results 151 to 160 of about 119,068 (185)
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The optical specificity of glutamine synthetase
Archives of Biochemistry and Biophysics, 1960The optical specificity of the glutamine synthetase isolated from dried peas has been studied. The degree of optical specificity shown by the enzyme is a function of the pH, the activating meta-lion concentration, the metal-ion species and the concentration of ammonia or hydroxylamine.
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Glutamine synthetase in the avian diencephalon
Journal of Experimental Zoology, 1973AbstractGlutamine synthetase (GS) activities are high in the nucleus rotundus of the avian diencephalon in late embryos and hatched chicks. The nucleus rotundus is known to be one component of a visual pathway in birds involving also the neural retina, the optic tectum and the cerebral ectostriatum.
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Glutamine synthetase deficiency
2020Prenatal onset malformations of the brain, seizures, necrolytic erythema of the skin, enteropathy with diarrhea, early neonatal death, and multiorgan failure or chronic encephalopathy and developmental delay, hyperammonemia, low concentration of glutamine in plasma and cerebrospinal fluid, and deficient activity of glutamine synthetase.
William L. Nyhan +3 more
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The Journal of Biochemistry, 1989
The nucleotide ligation site of adenylylated glutamine synthetase, which contains a unique tyrosyl residue linked through a phosphodiester bond to 5'-AMP, was studied by digestion with three hydrolytic enzymes. The products on micrococcal nuclease digestion were adenosine and o-phosphotyrosyl glutamine synthetase.
K, Kimura, Y, Nakano, K, Matsuoka
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The nucleotide ligation site of adenylylated glutamine synthetase, which contains a unique tyrosyl residue linked through a phosphodiester bond to 5'-AMP, was studied by digestion with three hydrolytic enzymes. The products on micrococcal nuclease digestion were adenosine and o-phosphotyrosyl glutamine synthetase.
K, Kimura, Y, Nakano, K, Matsuoka
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Journal of Bacteriology, 1967
The relationships of five feedback inhibitors for the Bacillus licheniformis glutamine synthetase were investigated. The inhibitors were distinguishable by differences in their competitive relationship for the substrates of the enzyme.
J S, Hubbard, E R, Stadtman
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The relationships of five feedback inhibitors for the Bacillus licheniformis glutamine synthetase were investigated. The inhibitors were distinguishable by differences in their competitive relationship for the substrates of the enzyme.
J S, Hubbard, E R, Stadtman
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Glutamine synthetase and hepatocarcinogenesis
Carcinogenesis, 1995R, Gebhardt, G M, Williams
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Inhibitors of Glutamine Synthetase
2002Due to the chemical inertness of the N2 molecule, the availability of metabolically accessible inorganic nitrogen sources was a key limiting factor for plant life on earth. The large scale conversion of N2 into NH3 and NO 3 - and their use as nitrogen fertilizer has been an agricultural standard for less than a century.
Guenter Donn, Helmut Köcher
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Glutamine synthetase and transferase
1967This enzyme (or enzymes) catalyzes the following reactions: 1. Glutamate + ATP + NH3 → glutamine + ADP + Pi (glutamine synthesis). 2. Glutamine + NH2OH →γ-glutamylhydroxamate + NH3 (glutamyl transfer reaction). 3. Glutamine + H2O → Glutamate + NH3 (arsenolysis of glutamine).
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Glutamine Synthetase as a Therapeutic Target for Cancer Treatment
International Journal of Molecular Sciences, 2021Dong Hoon Lee, So Hee Kwon, Gowoon Kim
exaly
[Glutamine synthetase immobilization].
Prikladnaia biokhimiia i mikrobiologiia, 1978Highly purified glutamine synthetase has been isolated from Chlorella and immobilized on BrCN-sepharose. Its residual activity was 25-35%. Immobilized glutamine synthetase showed far greater thermal stability than glutamine synthetase in solution. During immobilization pH optimum of the enzyme was shifted towards the alkaline area, maximum rate of the ...
A S, Rasulov, Z G, Evstigneeva
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