Results 191 to 200 of about 91,004 (324)

Glutamine synthetase-negative hepatocellular carcinoma has better prognosis and response to sorafenib treatment after hepatectomy. [PDF]

Chin Med J (Engl), 2023
Shao M, Tao Q, Xu Y, Xu Q, Shu Y, Chen Y, Shen J, Zhou Y, Wu Z, Chen M, Yang J, Shi Y, Wen T, Bu H.   +13 more
europepmc   +1 more source

Skeletal muscle metabolism in hypokinetic rats [PDF]

Muscle growth, protein metabolism, and amino acid metabolism were studied in various groups of rats. Certain groups were adrenaliectomized; some rats were suspended while others (the controls) were weight bearing. Results show that: (1) metabolic changes
Tischler, M. E.
core   +1 more source

Bifidobacterium longum subsp. longum CCFM1375 Mitigates Chronic Kidney Disease Progression via Gut Microbiota Modulation and Gut Barrier Restoration

Food Frontiers, Volume 7, Issue 1, January 2026.
(1) Bifidobacterium longum subsp. longum CCFM1375 restored gut barrier integrity by upregulating ZO‐1/ZO‐2 and suppressing IL‐6/TNF‐α, thereby reducing serum LPS and improving creatinine/BUN levels. (2) Reshaped gut microbiota: enriched beneficial species (Faecalibaculum rodentium, Asaccharobacter celatus, Adlercreutzia equolifaciens) while suppressing
Hongchao Wang, Xinchen Lv, Yue Zhang, Jinlin Zhu, Jia Hua, Bin Liu, Jianxin Zhao, Hao Zhang, Wei Chen, Wenwei Lu, Zhijian Zhang, Liang Wang   +11 more
wiley   +1 more source

Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement. [PDF]

Nat Commun, 2023
Ghosh S, Kundu R, Chandana M, Das R, Anand A, Beura S, Bobde RC, Jain V, Prabhu SR, Behera PK, Mohanty AK, Chakrapani M, Satyamoorthy K, Suryawanshi AR, Dixit A, Padmanaban G, Nagaraj VA.   +16 more
europepmc   +1 more source

Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate Metabolism

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Our research aimed to model primary hyperoxaluria type 1 in vitro using a stem cell model and assess the potential of adenine base editors in correcting the most common pathogenic AGXT genetic variant, c.508G>A (Gly170Arg), which leads to oxalate accumulation due to alanine‐glyoxylate aminotransferase mislocalization.
Timo Keskinen, Sami Jalil, Irem Gümüşoğlu, Juhana Juutila, Nadim Kestilä, Emilia Kuuluvainen, Ville Hietakangas, Diego Balboa, Kirmo Wartiovaara, Mervi E. Hyvönen   +9 more
wiley   +1 more source

Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1^-/- mice. [PDF]

iScience, 2023
Wang J, Gao Y, Xiao L, Lin Y, Huang L, Chen J, Liang G, Li W, Yi W, Lao J, Zhang B, Gao TM, Zhong M, Yang X.   +13 more
europepmc   +1 more source

Molecular Identification and Characterization of Cytosolic Isoforms of Glutamine Synthetase in Maize Roots

, 1996
Hitoshi Sakakibara, Hitoshi Shimizu, Toshiharu Hase, Yuzo Yamazaki, Toshifumi Takao, Yasutsugu Shimonishi, Tatsuo Sugiyama   +6 more
openalex   +1 more source

USP15 antagonizes CRL4 ^CRBN -mediated ubiquitylation of glutamine synthetase and neosubstrates

, 2021
Thang Van Nguyen
openalex   +2 more sources

Poa annua becomes the first weed to evolve resistance to indaziflam applied preemergence and early‐postemergence

Pest Management Science, Volume 82, Issue 1, Page 539-551, January 2026.
We report the first confirmed global case of Poa annua evolving resistance to indaziflam applied both preemergence and early‐postemergence. Resistance intensified under cool temperatures, was not reversed by metabolic inhibitors, and was often linked to multiple resistance, underscoring urgent needs for integrated weed management.
Joshua WA Miranda, Todd A Gaines, Marcelo L Moretti   +2 more
wiley   +1 more source

Glutamine synthetase shields triple-negative breast cancer cells from ferroptosis in metastasis triggered by glutamine deprivation. [PDF]

Breast Cancer Res
Yang Z, Lian X, Luo Y, Ye Q, Guo G, Liu G.   +5 more
europepmc   +1 more source