Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Syntheses and luminescent properties of a series of new lanthanide azelates [PDF]
A series of new lanthanide azelates [Ln(aze)(Haze)(H2O)]·H2O {Ln = La (1a), Ce (1b), Pr (1c); H2aze = azelaic acid}, [Ln2(aze)3(phen)2]·H2O [Ln = Nd (2a), Er (2b); phen = 1,10-phenanthroline], [Sm(aze)(Haze)(phen)]·2H2O (3), [Gd(aze)(phen)2]·ClO4 (4) and
Fu, Lianshe +4 more
core +1 more source
Adaptive resistance is not responsible for long-term drug resistance in a cellular model of triple negative breast cancer [PDF]
Resistance to cancer therapeutics represents a leading cause of mortality and is particularly important in cancers, such as triple negative breast cancer, for which no targeted therapy is available, as these are only treated with traditional ...
Castellanos-Uribe, M +3 more
core +2 more sources
New Catalytic Systems for Fixation of Carbon Dioxide into Valuable Poly(Alkylene Carbonates) [PDF]
Fixation of carbon dioxide into valuable products is a promising method to mitigate the issues of global warming and decrease the consumption of fossil-fuel carbon sources.
Bahramian, Bahareh, Dehghani, Fariba
core +2 more sources
Conversion of lanthanide glutarate chlorides with interstitial THF into lanthanide glutarates with unprecedented topologies [PDF]
Using slow diffusion methods at room temperature (RT), we obtained four isomorphous lanthanide glutarate chlorides, accommodating interstitial THF and water molecules, [Ln2(Glut)2Cl2(H2O)8]•2H2O•THF (1 - 4), with Ln = La (1), Ce (2), Pr (3), Nd (4). They
Dempsey, Christian +7 more
core +1 more source
An Efficient Process for Pretreatment of Lignocelluloses in Functional Ionic Liquids [PDF]
Background and Aims. The complex structure of the lignocelluloses is the main obstacle in the conversion of lignocellulosic biomass into valuable products. Ionic liquids provide the opportunities for their efficient pretreatment for biomass.
Bi-Xian Zhang +3 more
core +2 more sources
Desymmetrization of meso-methylenecyclopropanes by a palladium-catalyzed asymmetric ring-opening bis(alkoxycarbonylation) reaction [PDF]
Desymmetrization of various meso-methylenecyclopropanes was accomplished by a palladium-catalyzed asymmetric ring-opening bis(alkoxycarbonylation) reaction employing a chiral bioxazoline ligand. The reaction proceeded smoothly in the presence of copper(I)
Aratani Takahiro +5 more
core +2 more sources
Comprehensive metabolomic study of the response of HK-2 cells to hyperglycemic hypoxic diabetic-like milieu [PDF]
Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Although hyperglycaemia has been determined as the most important risk factor, hypoxia also plays a relevant role in the development of this disease.
Castro Puyana, María +5 more
core +1 more source
Multi-Omics to Illuminate Signaling Molecules of the Gut Microbiota-Brain Axis [PDF]
The human gastrointestinal (GI) tract harbors hundreds of trillions of microorganisms, collectively referred to as the gut microbiota. Complex, dynamic, and metabolically active by nature, these commensal microbes carry critical functional roles in ...
Lai, Yunjia
core +2 more sources
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng +19 more
wiley +1 more source

