Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [PDF]
BACKGROUND: Fibroblast growth factor 21 (FGF21), whose expression is induced by peroxisome proliferator-activated receptor alpha (PPARalpha), has been recently identified as a novel metabolic regulator which plays a crucial role in glucose homeostasis ...
Eder, Klaus+2 more
core +2 more sources
Enzymatic Logic Gates with Noise-Reducing Sigmoid Response [PDF]
Biochemical computing is an emerging field of unconventional computing that attempts to process information with biomolecules and biological objects using digital logic. In this work we survey filtering in general, in biochemical computing, and summarize the experimental realization of an AND logic gate with sigmoid response in one of the inputs.
arxiv
Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment [PDF]
Hydrocarbons are abundant in anoxic environments and pose biochemical challenges to their anaerobic degradation by microorganisms. Within the framework of the Priority Program 1319, investigations funded by the Deutsche Forschungsgemeinschaft on the ...
Boll, Matthias+22 more
core +2 more sources
Dependence of Substrate Irradiation Reaction Rate Stimulation on Lactic Dehydrogenase Source [PDF]
Stimulation of LDH initial reaction rates by timed pre-irradiation of crystalline sodium pyruvate and lithium lactate is reported for enzymes isolated from rabbit muscle, pig heart, human erythrocytes and chicken heart. The phenomenon investigated is referred to as the Comorosan effect.
arxiv
Stimulation of Enzyme Reaction Rates by Crystalline Substrate Irradiation: Dependence on Identity of Irradiated Substance [PDF]
The study reported here concerns a phenomenon, discovered and extensively investigated by Sorin Comorosan, wherein enzyme initial reaction rates are enhanced as a consequence of incorporation of solutions derived from previously irradiated crystalline material into the reaction medium.
arxiv
Biallelic mutations of the GCDH gene result in Glutaric Aciduria type 1 (GA1; OMIM #231670), an uncommon autosomal recessive inborn error caused by the deficiency of glutaryl-CoA dehydrogenase (CCDH), a mitochondrial matrix protein involved in the ...
Felix-Julian Campos-Garcia+8 more
doaj
Theoretic Insight into CO2 Reduction at Active Sites of Molybdenum and Tungsten Enzymes: a π Interaction between CO2 and Tungsten Bis-Dithiolene Complexes [PDF]
Active sites of molybdenum and tungsten enzymes, particularly mononuclear tungsten formate dehydrogenase (FDH) have been theoretically investigated towards their interaction with CO2. Obvious {\pi} interaction has been found between the 2e reduced metallodithiole moiety and the molecular CO2.
arxiv
Does renal GCDH expression contribute to the explanation of the two excretor types in glutaric aciduria type I? [PDF]
This Master Thesis was carried out at the University of Lausanne and is part of the master's curriculum in the School of Medicine(1). All manipulations have been done at the laboratory of the "Centre des Maladies Moléculaires" (CMM) which is part of the "
PARATA, G.
core
A clustering tool for nucleotide sequences using Laplacian Eigenmaps and Gaussian Mixture Models [PDF]
We propose a new procedure for clustering nucleotide sequences based on the "Laplacian Eigenmaps" and Gaussian Mixture modelling. This proposal is then applied to a set of 100 DNA sequences from the mitochondrially encoded NADH dehydrogenase 3 (ND3) gene of a collection of Platyhelminthes and Nematoda species.
arxiv
Analysis of Cellular Feature Differences of Astrocytomas with Distinct Mutational Profiles Using Digitized Histopathology Images [PDF]
Cellular phenotypic features derived from histopathology images are the basis of pathologic diagnosis and are thought to be related to underlying molecular profiles. Due to overwhelming cell numbers and population heterogeneity, it remains challenging to quantitatively compute and compare features of cells with distinct molecular signatures.
arxiv