Glutathione: overview of its protective roles, measurement, and biosynthesis.
Molecular Aspects of Medicine, 2009 H. Forman, Hongqiao Zhang, A. Rinna
semanticscholar +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
Advanced Science, EarlyView.This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao +8 more
wiley +1 more source
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway. [PDF]
Sci RepZhang J +12 more
europepmc +1 more source
A Complementarity‐Based Approach to De Novo Binder Design
Advanced Science, EarlyView.A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko +17 more
wiley +1 more source
Systemic Inflammatory Response Syndrome Following High-Dose Intravenous Glutathione-Containing Revitalising Solution in a Patient on Tirzepatide: A Case Report. [PDF]
CureusSharma D, Daram S, Sharma P.
europepmc +1 more source
The Glutathione Contents of Malignant Tumors, Especially the Rous Chicken Sarcoma
, 1926 H Yaoi, Waro Nakahara
openalex +2 more sources
Advanced Science, EarlyView.Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen +14 more
wiley +1 more source
Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione. [PDF]
CPT Pharmacometrics Syst PharmacolYang K +8 more
europepmc +1 more source