Results 241 to 250 of about 717,672 (315)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Redox metabolism in cell senescence: focusing on contributions from the metabolomic field. [PDF]

Front Mol Biosci
Chacón E, Grünwaldt G, Marmisolle I, Martínez J, Quijano C.   +4 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Commentary on "detoxification of deoxynivalenol by pathogen-inducible tau-class glutathione transferases from wheat". [PDF]

J Biol Chem
Shendre L.
europepmc   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Mechanisms of the marine yeast <i>Debaryomyces hansenii</i> for protection against reactive oxygen species produced during benzo(a)pyrene biotransformation. [PDF]

Appl Environ Microbiol
Padilla-Garfias F, Araiza-Villanueva MG, Calahorra M, Sánchez NS, Peña A.   +4 more
europepmc   +1 more source

Exogenous Glutathione and Nitric Oxide Improve Waterlogging Stress Tolerance in Maize. [PDF]

Plant Environ Interact
Angon PB, Tahjib-Ul-Arif M, Jahan MS, Hasan MM, Murata Y.   +4 more
europepmc   +1 more source

Broad-Spectrum Hepatoprotection by <i>Pteropyrum scoparium</i> Extract Against Multi-Pesticide Oxidative Stress in Rats. [PDF]

Foods
Al-Nasiri AM, Waly MI, Al-Alawi A, Al-Subhi L, Ali H, Al Zuhaibi K.   +5 more
europepmc   +1 more source