Results 91 to 100 of about 53,702 (285)
Role of glutathione transferases in herbicide detoxification in weeds [PDF]
, 1996 Glutathione transferases (GSTs) catalyse the conjugation of the electrophilic herbicides atrazine, metolachlor, alachlor and fluorodifen with the tripeptide glutathione (GSH).
Hatton, Pamela J., Hatton, P.J.
core
Glutathione disulfide accumulation at birth.
, 2013 Glutathione disulfide (GSSG) was measured in the lung and the liver of mice just before birth (time 0) and then 2 h, 6 h and 12 h after birth in room air and at similar times in the lungs of mice born in 10% oxygen.
Klaus H. Kaestner (123518) +5 more
core +1 more source
Advanced Science, EarlyView.Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu +10 more
wiley +1 more source
Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation
, 2010 During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
core
Characterisation of the oxidoreductase Erol-Lß and the misfolding of the secretory pathway substrate HLA-B27 [PDF]
, 2007 The endoplasmic reticulum (ER) is the site of oxidative folding for proteins entering the secretory pathway. Here, nascent polypeptides acquire disulfide bonds, which confer both stability and functionality on secretory and ER-resident proteins.
Lemin, Andrew James
core
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Advanced Science, EarlyView.Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
PLoS ONE, 2017 A search of the disulfide reductase activities expressed in the adult stage of the free-living platyhelminth Dugesia dorotocephala was carried out. Using GSSG or DTNB as substrates, it was possible to obtain a purified fraction containing both GSSG and ...
Alberto Guevara-Flores +5 more
doaj +1 more source
Glutathione-Sensitive Silicon Nanowire Arrays for Gene Transfection
, 2019 Ingenious surface modification strategies and special topological morphologies endow the biomaterial interface with excellent ability to regulate the cell fate. In this work, a gene delivery platform based on glutathione-sensitive silicon nanowire arrays
Yuping Liu (426572) +8 more
core +1 more source
Nature CommunicationsGlutaredoxins catalyze the reduction of disulfides and are key players in redox metabolism and regulation. While important insights were gained regarding the reduction of glutathione disulfide substrates, the mechanism of non-glutathione disulfide ...
Fabian Geissel +4 more
doaj +1 more source
Advanced Science, EarlyView.CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li +13 more
wiley +1 more source