Results 121 to 130 of about 48,461 (279)

Donor substrate specificity and thiol reduction of glutathione disulfide peroxidase.

, 1979
John W. Forstrom, Al L. Tappel
openalex   +1 more source

Synthesis of Unsymmetric Bis(heteroaryl) Selenides by Rhodium‐Catalyzed Exchange Reaction of Heteroaryl Fluorides and Ethers Using Se‐Heteroaryl Carboselenoates

European Journal of Organic Chemistry, EarlyView.
Various unsymmetric bis(heteroaryl) selenides are synthesized by the rhodium‐catalyzed exchange reaction of heteroaryl fluorides and ethers with Se‐heteroaryl 1‐adamatanecarboselenoates. The synthetic method is applicable to a broad range of five‐ and six‐membered heteroaryl derivatives and provides compounds containing multiple heteroatoms.
Masana Yazaki, Wei Han, Ren Suzuki, Mieko Arisawa   +3 more
wiley   +1 more source

The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG

, 2003
Miranda Verschraagen, Marc A. Kedde, Frederick H. Hausheer, W. J. F. van der Vijgh   +3 more
openalex   +2 more sources

X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment [PDF]

, 2019
Kirsty Line, Michail N. Isupov, E. James LaCourse, David Cutress, Russell M. Morphew, Peter M. Brophy, Jennifer A. Littlechild   +6 more
openalex   +1 more source

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

Exploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao, Yao Chen, Haimeng Yuan, Shuqian Yang, Hongyuan Zhang, Yuequan Wang, Shenwu Zhang, Qin Chen, Jin Sun, Zhonggui He, Cong Luo   +10 more
wiley   +1 more source

Synthesis of Alpha-Methylselenocysteine, Its Relevant Analogues, and an Unnatural Glutathione Disulfide Core

, 2020
Robert J. Wehrle
openalex   +1 more source

Targeting MGAT4A‐Mediated N‐Glycosylation as a Therapeutic Strategy to Inhibit Glioblastoma Stem Cell Invasion

Exploration, EarlyView.
ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu, Meichen Liu, Qingshan Yang, Jinlong Yin   +3 more
wiley   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

Protein disulfide isomerase plays a crucial role in mediating chemically-induced, glutathione depletion-associated hepatocyte injury in vitro and in vivo [PDF]

Yan-Yin Zhu, Qi Zhang, Yi-Chen Jia, Ming‐Jie Hou, Bao Ting Zhu   +4 more
openalex   +1 more source