Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley +1 more source
Thiolated Polymers in 3D Bioprinting: Control of Gelation. [PDF]
Haddadzadegan S +2 more
europepmc +1 more source
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
Failure of Hepatic Insulin Clearance via CEACAM1-Mediated Endocytosis: The Missing Physiological Link Between Proinsulin Misfolding, Hyperinsulinemia, and Metabolic Complications in Type 2 Diabetes, Obesity, and NAFLD. [PDF]
Akl MM, Ahmed A.
europepmc +1 more source
Crosstalk of thioredoxin system and programmed cell death: from pathophysiology to novel therapy. [PDF]
Wu Y +11 more
europepmc +1 more source
Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants. [PDF]
Goya-Iglesias N +7 more
europepmc +1 more source
The Mechanism and Regulation of Disulfidptosis and Its Role in Disease. [PDF]
Wan Y +7 more
europepmc +1 more source
A rapid HPLC method to simultaneously quantify therapeutic thiols and monitor their disulfide exchange reactions with cystine. [PDF]
Hadjipour A +3 more
europepmc +1 more source
Impact of Reducing Agents on Protein Synthesis in a Reconstituted Cell-Free Protein Synthesis System. [PDF]
Fuse-Murakami T +9 more
europepmc +1 more source
Disulfidptosis: A Metabolic Cell Death Mechanism with Therapeutic Potential in Cancer. [PDF]
Zhao W, Wang Q, Zhang J.
europepmc +1 more source

