Results 141 to 150 of about 487,455 (339)
Inspired by human pulmonary cilia and their mucus defend against bacteria, nanozyme‐centric hydrogel networks have been assembled into nanowires, combining the rapid penetration capability of the nanowire arrays with the adhesion and detection functions of the nanozyme‐centric hydrogel networks.
Zhaoling Tan+4 more
wiley +1 more source
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang+10 more
wiley +1 more source
Background: The etiology and pathophysiologic mechanism of vitiligo are still unclear. The relationship between increased oxidative stress due to the accumulation of radicals and reactive oxygen species and the associated changes in blood and epidermal ...
Ozturk I+4 more
doaj
Long-term supplementation with selenate and selenomethionine: Selenium and glutathione peroxidase (EC1.11.1.9) in blood components of New Zealand women [PDF]
Christine D. Thomson+3 more
openalex +1 more source
DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training
DeepSecMS, a deep learning platform leveraging a Cys‐to‐Sec proxy training strategy, enhances the identification of known selenoproteins and holds promise for discovering novel candidates. This proxy approach overcomes limitations associated with the rarity of known selenoproteins and demonstrates broad applicability in studying other rare protein ...
Chenfang Si+5 more
wiley +1 more source
Effects of variation in glutathione peroxidase activity on DNA damage and cell survival in human cells exposed to hydrogen peroxide and t-butyl hydroperoxide [PDF]
B Sandström, Stefan L. Marklund
openalex +1 more source
We designed a copper‐based nanotube (NT) with copper ionophores to induce enhanced cuproptosis. In combination with starvation therapy, the NT significantly inhibited energy metabolism in HCC cells. Our results show that the depletion of GSH by Cu2+ intensified oxidative stress and cuproptosis, resulting in ROS generation and DLAT aggregation ...
Xuan Han+8 more
wiley +1 more source
Structural organization and regulation of the gene for the androgen- dependent glutathione peroxidase-like protein specific to the mouse epididymis [PDF]
Norbert B. Ghyselinck
openalex +1 more source
Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves+17 more
wiley +1 more source