Results 191 to 200 of about 508,182 (337)
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.
Cell Metabolism, 2008 A. Seiler, Manuela Schneider, H. Förster, Stephan Roth, E. Wirth, C. Culmsee, N. Plesnila, E. Kremmer, O. Rådmark, W. Wurst, G. Bornkamm, U. Schweizer, M. Conrad +12 moresemanticscholar +1 more sourceReprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis
Advanced Science, EarlyView.SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu +16 morewiley +1 more sourceGlutathione peroxidase 4 as a potential biomarker for atrial fibrosis and recurrence of atrial fibrillation. [PDF]
Heart Rhythm O2Liu T, Zhou DT, Liu F, Long DY, Yang Y, Li MM, Zhao X, Li CY, Wang W, Jiang CX, Tang RB. +10 moreeuropepmc +1 more sourceLipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1 [PDF]
, 2015 Ewa Jabłońska, Jolanta Gromadzińska, Beata Pepłońska, Wojciech Fendler, Edyta Reszka, Magdalena Beata Król, Edyta Wieczorek, Agnieszka Bukowska, Peter Grešner, Michał Galicki, Oskar Zambrano Quispe, Zbigniew Morawiec, Wojciech Wąsowicz +12 moreopenalex +1 more sourceDependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Nature, 2017 V. Viswanathan, M. Ryan, Harshil Dhruv, S. Gill, Ossia M. Eichhoff, B. Seashore-Ludlow, S. Kaffenberger, J. Eaton, K. Shimada, A. Aguirre, S. Viswanathan, S. Chattopadhyay, P. Tamayo, W. Yang, M. Rees, Sixun Chen, Z. Boskovic, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, E. Roider, D. Gao, J. Cleary, B. Wolpin, J. Mesirov, D. Haber, J. Engelman, J. Boehm, J. Kotz, C. Hon, Yu Chen, W. Hahn, M. Levesque, John G Doench, M. Berens, Alykhan F. Shamji, P. Clemons, B. Stockwell, S. Schreiber +39 moresemanticscholar +1 more sourceAsymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections
Advanced Science, EarlyView.To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu +9 morewiley +1 more sourceGlutathione peroxidase 3 is a potential biomarker for konzo. [PDF]
Nat CommunBramble MS, Fourcassié V, Vashist N, Roux-Dalvai F, Zhou Y, Bumoko G, Kasendue ML, Spencer D, Musasa Hanshi-Hatuhu H, Kambale-Mastaki V, Manalo RVM, Mohammed A, McIlwain DR, Cunningham G, Summar M, Boivin MJ, Caldovic L, Vilain E, Mumba-Ngoyi D, Tshala-Katumbay D, Droit A. +20 moreeuropepmc +1 more source
