Results 191 to 200 of about 167,749 (264)

The role of glutathione peroxidase 4 in the progression, drug resistance, and targeted therapy of non-small cell lung cancer. [PDF]

Oncol Res
Wei J, Zhu L.
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth. [PDF]

J Biol Eng
Teferi N, Ekanayake A, Owusu SB, Moninger TO, Sarkaria JN, Tivanski AV, Petronek MS.   +6 more
europepmc   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Efficacy of Huoxue Tongqiao Decoction combined with aniracetam in treating post-stroke cognitive impairment in elderly patients with ischemic stroke and its effects on serum levels of superoxide dismutase, glutathione peroxidase and nitric oxide. [PDF]

Pak J Med Sci
Xu J, Bai X, Wang H, Li J, Cai P.
europepmc   +1 more source

Metal‐Free Ligand‐Centered Radical Scavenging in Pyridine‐Modified Tetraaza Macrocycles

European Journal of Organic Chemistry, EarlyView.
Ligand‐centered hydrogen‐atom transfer in pyridinophane macrocycles generates delocalized radicals, with Py2N2 enabling cooperative captodative stabilization and enhanced DPPH• quenching. Pyridine‐modified tetraaza macrocycles are widely studied as ligand platforms for metal coordination, yet their intrinsic redox and radical reactivity in the absence ...
Christina Mantsorov, Hannah K. Pyle, Tahmina Afroz, Caden‐Jack N. Walls, Nora Del Bosque, Timothy M. Schwartz, Chelsea N. Miller, Kristof Pota, Benjamin G. Janesko, Kayla N. Green   +9 more
wiley   +1 more source

Inhibition of glutathione peroxidase 4 suppresses gastric cancer peritoneal metastasis via regulation of RCC2 homeostasis. [PDF]

Redox Biol
Hu C, Xu J, Zhang Y, Zhang R, Pan S, Chen J, Wang Y, Zhao Q, Wang Y, Zhu W, Cao M, Zhang S, Zu D, Xu Z, Jing J, Cheng X.   +15 more
europepmc   +1 more source

Transcutaneous auricular vagus nerve stimulation improves emotional and cognitive functions in post-traumatic stress disorder rats through anti-inflammation, neuroprotection, and modulation of the hippocampal nuclear factor erythroid 2-related factor 2-heme oxygenase-1-glutathione peroxidase 4 pathway. [PDF]

J Tradit Chin Med
Yanfeng Z, Xinjiang Z, Xiaomeng Z, Xiangji LI, Chen X, Jingwei K, Xin W, Lan S, Peijing R.   +8 more
europepmc   +1 more source

Assessment of glutathione peroxidase 1 and 4 expression in oral squamous cell carcinoma patients in a tertiary care center: A comparative cross-sectional study. [PDF]

J Taibah Univ Med Sci
Farooqi S, Akbar Ansari S, Danish F, Fatima Khan R, Ali Muhammad A, Zaman A.   +5 more
europepmc   +1 more source

Deficiency in glutathione peroxidase 4 (GPX4) results in abnormal lens development and newborn cataract. [PDF]

Proc Natl Acad Sci U S A
Wei Z, Hao C, Radeen KR, Hao Z, Kettimuthu K, Maner-Smith K, Toyokuni S, Fan X.   +7 more
europepmc   +1 more source