Nimesulide limits kainate-induced oxidative damage in the rat hippocampus [PDF]
Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen species, we investigated the effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on kainate-induced in vivo oxidative damage in the rat hippocampus.
arxiv
On the active site of the NADPH‐dependent CoA‐SS‐Glutathione reductase from yeast and rat liver [PDF]
Raúl N. Ondarza, Rebeca Abney
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Protocol for measuring erythrocyte glutathione reductase activity coefficient to assess riboflavin status. [PDF]
Parkington DA, Koulman A, Jones KS.
europepmc +1 more source
Superoxide reductase from Desulfoarculus baarsii: reaction mechanism and role of glutamate 47 and lysine 48 in catalysis [PDF]
Superoxide reductase (SOR) is a small metalloenzyme that catalyzes reduction of O(2)(*)(-) to H(2)O(2) and thus provides an antioxidant mechanism against superoxide radicals. Its active site contains an unusual mononuclear ferrous center, which is very efficient during electron transfer to O(2)(*)(-) [Lombard, M., Fontecave, M., Touati, D., and Nivi ...
arxiv
Protection of phagocytic leukocytes by endogenous glutathione: studies in a family with glutathione reductase deficiency [PDF]
Dirk Roos+6 more
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Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Gene knockout of glutathione reductase results in increased sensitivity to heavy metals in Acidithiobacillus caldus. [PDF]
Shi Y+7 more
europepmc +1 more source
Coordinated transcriptional regulation between a reactive oxygen species-responsive gene network and the circadian clock in Arabidopsis thaliana : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Plant Biology at Massey University, Plant Biology, New Zealand [PDF]
Most organisms have evolved endogenous biological clocks as internal timekeepers to fine-tune physiological processes to the external environment. Energetic cycles such as photosynthesis and glycolytic cycles are physiological processes that have ...
Lai, Alvina Grace
core
Interrelationship of glutathione–cystine transhydrogenase and glutathione reductase in developing rat intestine [PDF]
Beatrice States, Stanton Segal
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We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao+9 more
wiley +1 more source