Results 251 to 260 of about 151,919 (337)

Dietary Selenium Deficiency Accelerates the Onset of Aging‐Related Gut Microbial Changes in Aged Telomere‐Humanized Mice, With Akkermansia muciniphila Being the Most Prominent and Alleviating Selenium Deficiency‐Induced Type 2 Diabetes

open access: yesAging Cell, EarlyView.
Gut Akkermansia muciniphila is enriched by dietary selenium deficiency in aged telomere‐humanized mice and counteracts dietary selenium deficiency‐induced type 2 diabetes. ABSTRACT Previous studies have shown that dietary selenium (Se) deficiency in mice reshapes gut microbiota, exacerbates healthspan deterioration (e.g., type 2 diabetes), and ...
Ying‐Chen Huang   +16 more
wiley   +1 more source

Glutathione Reductase Expression and Its Prognostic Significance in Colon Cancer. [PDF]

open access: yesInt J Mol Sci
Brzozowa-Zasada M   +7 more
europepmc   +1 more source

Altered Relaxation and Mitochondria‐Endoplasmic Reticulum Contacts Precede Major (Mal)Adaptations in Aging Skeletal Muscle and Are Prevented by Exercise

open access: yesAging Cell, EarlyView.
Slowed relaxation and altered MERCs embody early stages of aging in muscle, and are prevented by regular exercise. ABSTRACT Sarcopenia, or age‐related muscle dysfunction, contributes to morbidity and mortality. Besides decreases in muscle force, sarcopenia is associated with atrophy and fast‐to‐slow fiber type switching, which is typically secondary to
Ryan J. Allen   +9 more
wiley   +1 more source

Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa

open access: yesAndrology, EarlyView.
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa   +2 more
wiley   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

Inhibition of trypanothione reductase and glutathione reductase by ferrocenic 4-aminoquinoline ureas

open access: yesARKIVOC, 2008
Margaret A.L. Blackie   +3 more
doaj   +1 more source

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