Results 261 to 270 of about 151,919 (337)

Fragment library screening by X-ray crystallography and hit optimization against thioredoxin glutathione reductase of Schistosoma mansoni

, 2023
Neto LRS, Montoya BO, Moreira-Filho JT, Brandão-Neto J, Verma A, Bowyer S, Dantas RF, Neves BJ, Delft F, Owens RJ, Furnham N, Andrade CH, Silva FP.   +12 more
europepmc   +1 more source

Selenium supplementation acting through the induction of thioredoxin reductase and glutathione peroxidase protects the human endothelial cell line EAhy926 from damage by lipid hydroperoxides [PDF]

, 2002
Michelle Lewin, John R. Arthur, Rudolph A. Riemersma, Fergus Nicol, Simon W. Walker, E.Margaret Millar, A. Forbes Howie, Geoffrey J. Beckett   +7 more
openalex   +1 more source

Corrigendum: Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme. [PDF]

Front Mol Biosci
Smith MM, Moran GR.
europepmc   +1 more source

Nuclear and Nucleolar Glutathione Reductase, Peroxidase, and Transferase Activities in Livers of Male and Female Fischer-344 Rats [PDF]

, 2002
Lynette K. Rogers
openalex   +1 more source

Ectopic suicide inhibition of thioredoxin glutathione reductase. [PDF]

Free Radic Biol Med, 2020
Silvestri I, Lyu H, Fata F, Banta PR, Mattei B, Ippoliti R, Bellelli A, Pitari G, Ardini M, Petukhova V, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F.   +13 more
europepmc   +1 more source

Silver Organometallics that are Highly Potent Thioredoxin and Glutathione Reductase Inhibitors: Exploring the Correlations of Solution Chemistry with the Strong Antibacterial Effects. [PDF]

ACS Infect Dis
Esarev IV, Karge B, Zeng H, Lippmann P, Jones PG, Schrey H, Brönstrup M, Ott I.   +7 more
europepmc   +1 more source

The Carba Mix—In Vitro Investigations of Potential Cocktail Effects in Patch Tests With Rubber Allergens

Contact Dermatitis, EarlyView.
The carba mix was studied in a human cell model to better understand human patch reactions to the mix. Our results support that the carba mix can give rise to cocktail effect and that patch testing with separate carba mix sensitisers may thus be more appropriate.
Linda Ljungberg Silic, Renato Ivan de Ávila, Sofía Carreira‐Santos, Gábor Merényi, Ola Bergendorff, Kathrin S. Zeller   +5 more
wiley   +1 more source

A Physiological Approach to Explore How Thioredoxin-Glutathione Reductase (TGR) and Peroxiredoxin (Prx) Eliminate H₂O₂ in Cysticerci of Taenia. [PDF]

Antioxidants (Basel)
Guevara-Flores A, Nava-Balderas G, de Jesús Martínez-González J, Vásquez-Lima C, Rendón JL, Del Arenal Mena IP.   +5 more
europepmc   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. [PDF]

ACS Infect Dis, 2020
Lyu H, Petukhov PA, Banta PR, Jadhav A, Lea WA, Cheng Q, Arnér ESJ, Simeonov A, Thatcher GRJ, Angelucci F, Williams DL.   +10 more
europepmc   +1 more source