Results 321 to 330 of about 147,440 (362)

Enhancing Tolerance to Combined Heat and Drought Stress in Cool‐Season Grain Legumes: Mechanisms, Genetic Insights, and Future Directions

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT The increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L ...
Manu Priya   +2 more
wiley   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Exploring experimental models of prostate cancer in chemoprevention: Oxidative stress as a key pathway to translational research

open access: yesPathology International, Volume 75, Issue 3, Page 131-144, March 2025.
Animal models are essential for understanding and preventing cancer progression. The TRAP (Transgenic Rat for Adenocarcinoma of the Prostate) model effectively mirrors human prostate cancer (PCa) progression, demonstrating the roles of androgen receptor signaling and oxidative stress in PCa development and the transition to castration‐resistant ...
Aya Naiki‐Ito   +2 more
wiley   +1 more source

Dark side of anthocyanin pigmentation

open access: yesPlant Biology, EarlyView.
This review examines dark anthocyanin pigmentation in plants by outlining its distribution, exploring the genetic mechanisms behind its development, and discussing its ecological role together with its potential for various industrial applications. Abstract Dark pigmentation can be observed in various parts of the plant, ranging from foliage to petals ...
K. Wolff, B. Pucker
wiley   +1 more source

Auranofin Induces ER Stress‐Mediated Apoptosis, and Its Combination With Bortezomib Elicits Paraptosis‐Like Cell Death in Malignant Canine Mammary Tumour Cells

open access: yesVeterinary and Comparative Oncology, EarlyView.
A schematic representation summarises the key findings of the study. In Auranofin (AF)‐sensitive canine mammary tumour (CMT) cells, treatment with 0.5–2 μM AF induces moderate endoplasmic reticulum (ER) stress via thioredoxin reductase (TrxR) inhibition, leading to ER stress‐mediated apoptosis.
Yoon‐Ho Suh   +6 more
wiley   +1 more source

Parasitic success of the pathogenic plant Phelipanche ramosa (L.) Pomel. (Orobanchaceae) differs in some re‐infected versus naïve tomato cultivars

open access: yesWeed Research, Volume 65, Issue 2, March/April 2025.
Abstract Plants are exposed to infection and predation by organisms from most kingdoms of life, including their own. Layers of molecular defence mechanisms have evolved to limit damage and disease from microbial and insect pathogens, and plants can also defend themselves against attack by members of their own kingdom.
Julia K. H. Leman   +3 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi   +9 more
wiley   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu   +7 more
wiley   +1 more source

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