Results 181 to 190 of about 166,309 (308)

Biomimetic TME‐Responsive Nanotheranostics for Precise NIR‐II Ratiometric Photoacoustic Imaging and Synergistic Immuno‐Photothermal Therapy

open access: yesSmall, EarlyView.
A biomimetic Au/Ag@HMON‐NLG@CCM nanotheranostic is engineered for tumor microenvironment‐responsive NIR‐II ratiometric photoacoustic imaging and immune‐photothermal therapy. The integration of hyperthermia‐triggered immunogenic cell death with IDO‐blockade‐mediated metabolic remodeling promotes dendritic cell maturation and T‐cell activation.
Xin Li   +9 more
wiley   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

open access: yesThe Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior   +10 more
wiley   +1 more source

Prevalence of Glutathione-S-Transferase T and M Deletion Polymorphisms in Apical Periodontitis: a Two-Center Observational Study. [PDF]

open access: yesActa Stomatol Croat
Kadic M   +8 more
europepmc   +1 more source

Comprehensive Evaluation of Bisphenol A Toxicity Reveals Neurobehavioral, Metabolic, and Reproductive Impairments in Girardia tigrina

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a common industrial chemical used in plastics and consumer products, is increasingly detected in aquatic environments, raising serious concerns about its potential ecological impacts. This study evaluated the sublethal and acute toxic effects of BPA on the freshwater planarian Girardia tigrina, a recognized model for ...
Raquel de Jesus Selestrino   +2 more
wiley   +1 more source

Multistressor Interaction of Perfluorooctane Sulfonate (PFOS) and Temperature in Two Estuarine Fish Species, Red Drum (Sciaenops ocellatus) and Sheepshead Minnow (Cyprinodon variegatus)

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Perfluorooctane sulfonate (PFOS), a perfluoroalkyl substance (PFAS), is characterized by a long, fluorinated carbon chain which makes it ideal for oil‐ and water‐repellent products but detrimental for the environment, where it persists and accumulates in organisms.
Anna L. Thornton   +5 more
wiley   +1 more source

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