Results 11 to 20 of about 21,538,465 (192)

Toxicity induced by Solanapyrone A in Chickpea shoots and its metabolism through Glutathione/Glutathione-S-Transferase system [PDF]

open access: yes, 2013
Solanapyrone A and C were isolated from a Pakistani isolate of Ascochyta rabiei, Pk-1. Two experiments were conducted to investigate the phytotoxic effects of the most potent toxin, solanapyrone A on chickpea cultivars and its subsequent detoxification ...
Riaz, A.   +5 more
core   +7 more sources

The role of glutathione transferases in TNT detoxification [PDF]

open access: yes, 2012
Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
core   +6 more sources

Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast [PDF]

open access: yes, 2015
Glutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive.
Bellamy, C O, Harrison, D J
core   +2 more sources

Metabolism of hydroperoxy-phospholipids in human hepatoma HepG2 cells

open access: yesJournal of Lipid Research, 1996
Two enzymatic mechanisms have been proposed for the metabolism of hydroperoxy-phospholipids: i) the combined action of phospholipase A2 and glutathione peroxidase, and/or ii) direct enzymatic reduction.
Y Bao, G Williamson
doaj   +1 more source

Reversal of hypermethylation and reactivation of glutathione -transferase pi 1 gene by curcumin in breast cancer cell line

open access: yesTumor Biology, 2017
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor.
Umesh Kumar   +2 more
doaj   +1 more source

The Role of Glutathione Transferases in the Detoxification of TNT [PDF]

open access: yes, 2010
Manufacture, use, storage and improper disposal of the explosive 2,4,6-trinitrotoluene (TNT) have led to widespread, global contamination of soil and groundwater.
Sparrow, Helen
core   +6 more sources

Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants

open access: yesPlant Protection Science, 2004
Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it.
Lyuba P.-E. Miteva   +3 more
doaj   +1 more source

"INHIBITION ASSAY STUDY OF PURIFIED GLUTATHIONE S-TRANSFERASE FROM FASCIOLA HEPATICA AND SHEEP LIVER TISSUE BY HEXACHLOROPHENE" [PDF]

open access: yesActa Medica Iranica, 2004
Glutathione S-transferases (GSTs) are widespread in Fasciola. hepatica parasite and sheep liver tissue. Study of GSTs inhibition assays in F. hepatica and sheep liver tissue are a priority of chemotherapeutic targets in parasitic liver diseases including
A. Farahnak PM. Brophy
doaj   +2 more sources

Glutathione S-Transferase Enzymes in Plant-Pathogen Interactions

open access: yesFrontiers in Plant Science, 2018
Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes encoded by large gene families. A characteristic feature of GST genes is their high inducibility by a wide range of stress conditions including biotic stress.
Gábor Gullner   +3 more
doaj   +1 more source

Genetic Polymorphism of GSTP-1 Affects Cyclophosphamide Treatment of Autoimmune Diseases

open access: yesMolecules, 2020
Cyclophosphamide is one of the most potent and reliable anti-cancer and immunosuppressive drugs. In our study, 33 individuals with different autoimmune diseases were treated with cyclophosphamide according to standard protocols.
Péter Hajdinák   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy