Results 21 to 30 of about 223,295 (334)

Glutathione and glutathione S-transferases in Barrett's epithelium [PDF]

British Journal of Cancer, 1993
Glutathione content, enzyme activity and isoenzyme composition of glutathione S-transferases were assayed in normal and Barrett's esophageal epithelium of ten patients with Barrett's esophagus. In addition, gastric and duodenal specimens from the same patients were also investigated.
W H, Peters, H M, Roelofs, M P, Hectors, F M, Nagengast, J B, Jansen   +4 more
openaire   +2 more sources

A glutathione s-transferase confers herbicide tolerance in rice [PDF]

Crop Breeding and Applied Biotechnology, 2014
Plant glutathione S-transferases (GSTs) have been a focus of attention due to their role in herbicide detoxification. OsGSTL2 is a glutathione S-transferase, lambda class gene from rice (Oryza sativa L.).
Tingzhang Hu
doaj   +1 more source

Glutathione S-Transferase Activity in Tissues of Rats Exposed to Fenarimol

Brazilian Archives of Biology and Technology, 2021
The unconscious use of pesticides causes various adverse effects on non-target organisms, including humans. Enzymes that control metabolism become the target of the pesticide and the organs are damaged due to toxic effects. Glutathione s-transferase (GST,
Halime Ozcelebi, Ferda Ari, Egemen Dere
doaj   +1 more source

Targeting glutathione S-transferase M4 in Ewing sarcoma

Frontiers in Pediatrics, 2014
Ewing sarcoma is a malignant pediatric bone and soft tissue tumor. Although the 5-year survival rate of localized disease approaches 75%, the prognosis of metastatic and/or therapy-resistant disease remains dismal despite the wide use of aggressive ...
Rupeng eZhuo, kenneth ekosak, savita esankar, Elizabeth T Wiles, Ying eSun, Jianxing eZhang, Janet eAyello, Glenn ePrestwich, Paul eShami, Mitchell S Cairo, Stephen eLessnick, Wen eLuo   +11 more
doaj   +1 more source

Genetic Polymorphism of GSTP-1 Affects Cyclophosphamide Treatment of Autoimmune Diseases

Molecules, 2020
Cyclophosphamide is one of the most potent and reliable anti-cancer and immunosuppressive drugs. In our study, 33 individuals with different autoimmune diseases were treated with cyclophosphamide according to standard protocols.
Péter Hajdinák, Melinda Szabó, Emese Kiss, Lili Veress, Lívius Wunderlich, András Szarka   +5 more
doaj   +1 more source

Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor

Nature Communications, 2016
Glutathione S-transferase omega 1 (GSTO1) is an atypical GST isoform that is overexpressed in several cancers and has been implicated in drug resistance. Currently, no small-molecule drug targeting GSTO1 is under clinical development.
K. Ramkumar, S. Samanta, A. Kyani, Suhui Yang, S. Tamura, Elizabeth K Ziemke, J. Stuckey, Si Li, Krishnapriya Chinnaswamy, Hiroyuki Otake, Bikash Debnath, V. Yarovenko, J. Sebolt-Leopold, M. Ljungman, N. Neamati   +14 more
semanticscholar   +1 more source

Effect of Chronic Exposure to Pesticide Methomyl on Antioxidant Defense System in Testis of Tilapia (Oreochromis niloticus) and Its Recovery Pattern

Applied Sciences, 2021
The chronic effect of environmental methomyl on the antioxidant system in testis of Nile tilapia (Oreochromis niloticus) and its recovery pattern was investigated.
Shunlong Meng, Xi Chen, Chao Song, Limin Fan, Liping Qiu, Yao Zheng, Jiazhang Chen, Pao Xu   +7 more
doaj   +1 more source

Identification of a diazinon-metabolizing glutathione S-transferase in the silkworm, Bombyx mori

Scientific Reports, 2016
The glutathione S-transferase superfamily play key roles in the metabolism of numerous xenobiotics. We report herein the identification and characterization of a novel glutathione S-transferase in the silkworm, Bombyx mori.
Kohji Yamamoto, N. Yamada
semanticscholar   +1 more source

Transgenic Arabidopsis Plants Expressing Tomato Glutathione S-Transferase Showed Enhanced Resistance to Salt and Drought Stress

PLoS ONE, 2015
Although glutathione S-transferases (GST, EC 2.5.1.18) are involved in response to abiotic stress, limited information is available regarding gene function in tomato.
Jing Xu, X. Xing, Yong-Sheng Tian, R. Peng, Yong Xue, Wei Zhao, Q. Yao   +6 more
semanticscholar   +1 more source

Serum Paraoxonase, Arylesterase, and Glutathione-S-Transferase Activities and Oxidative Stress Levels in Patients with Mushroom Poisoning

Clinics, 2018
OBJECTIVES: Consumption of toxic species of mushrooms may have detrimental effects and increase oxidative stress. Paraoxonase, arylesterase and glutathione-S-transferase are antioxidants that resist oxidative stress.
Sevki Hakan Eren, Ilhan Korkmaz, Fatma Mutlu Kukul Guven, Yusuf Kenan Tekin, Levent Ozdemir   +4 more
doaj   +1 more source