Results 131 to 140 of about 21,521,606 (315)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Glutathione transferases: new functions

, 2005
Well known as detoxification enzymes, the glutathione transferases also function in prostaglandin and steroid hormone synthesis. New uses for the canonical glutathione transferase fold are becoming apparent; the bacterial stringent starvation protein ...
Aaron Oakley (19584748)
core   +1 more source

Susceptibility of Different Egyptian Populations of Tuta absoluta (Meyrick) to Selected Insecticides and Associated Detoxification Enzyme Activities

Insects
The tomato borer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae), is a highly destructive invasive pest of tomato, and its ability to develop resistance to insecticides is well known.
Ahmed M. M. Ahmed, Lenni Ramirez-Flores, Mohammed A. A. Saad, Ahmed A. Alsherbiny, Hosam A. Ezz El-Din, Reda E. Korat, Nihal M. M. Khalil Bagy, Verónica Andrade-Yucailla, Marcos Barros-Rodríguez   +8 more
doaj   +1 more source

Antennal transcriptomic analysis of carboxylesterases and glutathione S-transferases associated with odorant degradation in the tea gray geometrid, Ectropis grisescens (Lepidoptera, Geometridae). [PDF]

Front Physiol, 2023
Zhang F, Chen Y, Zhao X, Guo S, Hong F, Zhi Y, Zhang L, Zhou Z, Zhang Y, Zhou X, Li X.   +10 more
europepmc   +1 more source

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

Advanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo, Wei Zhuang, Zean Li, Yiming Lai, Yongyi Ou, Dongquan Li, Shanhe Huang, Tianlong Luo, Jintao Hu, Bingliang Chen, Jianhan Fu, Tao Zhuo, Hankun Jiang, Yin Lu, Hai Huang, Kewei Xu, Shengmeng Peng, Qing Yuan   +17 more
wiley   +1 more source

Thymoquinone effect on the Dictyostelium discoideum model correlates with functional roles for glutathione S-transferases in eukaryotic proliferation, chemotaxis, and development. [PDF]

PLoS One, 2023
Alsaffar N, Fang Y, Walters E.
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Genome-wide identification of the GST reveals ZmGST1 enhances the resistance to Exserohilum turcicum in maize

BMC Plant Biology
Background Northern corn leaf blight is caused by Exserohilum turcicum and poses a significant threat to maize yields. Therefore, it is of vital importance to explore disease-resistant genes and cultivate disease-resistant varieties.
Hanqiao Wang, Yuhang Zhang, Meiyi Liu, Xiangyu Xing, Mingrui Li, Zhiqiang Wu, Zixin Zhang, Qingfeng Li, Heng Pan, Wei Yang, Jiabin Ci, Xuejiao Ren, Liangyu Jiang, Zhenyuan Zang   +13 more
doaj   +1 more source

Identification and Functional Analysis of Glutathione S-Transferases from Sitophilus zeamais in Olfactory Organ. [PDF]

Insects, 2022
Xia D, Zheng R, Huang J, Lu S, Tang Q.
europepmc   +1 more source

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source