Indomethacin inhibition of glutathione S-transferases
Indomethacin inhibited rat liver glutathione S-transferases (EC 2.5.1.18). Its inhibition was non-competitive with respect to 3,4-dichloronitrobenzene with an apparent Ki of 5.3 x 10-5 M and uncompetitive with respect to glutathione with an apparent Ki
Wu, Chung +3 more
core +1 more source
The expression of GST isoenzymes and p53 in non-small cell lung cancer.
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients.
MĂźzeyyen Ozhavzali +6 more
doaj +1 more source
The Role of Glutathione Transferases in the Detoxification of TNT [PDF]
Manufacture, use, storage and improper disposal of the explosive 2,4,6-trinitrotoluene (TNT) have led to widespread, global contamination of soil and groundwater.
Sparrow, Helen
core
Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Glutathione S-transferases (GSTs) are detoxification enzymes involved in the metabolism of numerous chemotherapeutic drugs. Overexpression of GSTs is correlated with cancer chemotherapy resistance.
Ansari Djaberi, Marc Georges +2 more
core +1 more source
The regulation of glutathione s-transferases by gibberellic acid application in salt treated maize leaves. [PDF]
Seckin Dinler B, Cetinkaya H, Secgin Z.
europepmc +1 more source
Functional analysis of the glutathione S-transferases from Thinopyrum and its derivatives on wheat Fusarium head blight resistance. [PDF]
Guo X +12 more
europepmc +1 more source
Polymorphism of the glutathione S-transferases in prostate cancer
Prostate cancer occurs more and more frequently in men over 50 years of age. Its etiology is still unclear, despite numerous studies of its main risk factors. Scientists discovered, that it is genetically and environmentally determined.
Kamiński, Piotr +3 more
core +1 more source
Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation. [PDF]
Koirala B K S, Moural T, Zhu F.
europepmc +1 more source
Glutathione transferases: new functions
Well known as detoxification enzymes, the glutathione transferases also function in prostaglandin and steroid hormone synthesis. New uses for the canonical glutathione transferase fold are becoming apparent; the bacterial stringent starvation protein ...
Aaron Oakley (19584748)
core
cDNA clones for glutathione S-transferases A (GST-A) and A1 (GST-A1) from plaice (Pleuronectes platessa) were expressed as N-terminally 6XHis tagged proteins in Escherichia coli and purified to homogeneity from Ni-NTA silica.
George, Stephen +2 more
core +1 more source

