Results 91 to 100 of about 148,506 (307)
The influence of glutathione S-transferases M1 and M3 on the development of bladder cancer [PDF]
Problem: Cigarette smoking is the most important risk factor of transitional cell carcinoma of the urinary bladder. The effect of the glutathione S- transferases M1 (GSTM1) and M3 (GSTM3) on the influence of this risk factor was investigated.
Golka, Klaus +3 more
core
Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]
, 1993 A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Seißler, Jochen +4 more
core +1 more source
Inactivation of Anopheles gambiae Glutathione Transferase ε2 by Epiphyllocoumarin
Biochemistry Research International, 2016 Glutathione transferases (GSTs) are part of a major family of detoxifying enzymes that can catalyze the reductive dehydrochlorination of dichlorodiphenyltrichloroethane (DDT).
Patience Marimo +2 more
doaj +1 more source
Glutathione S-conjugates as prodrugs to target drug-resistant tumors
Frontiers in Pharmacology, 2014 Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic detoxification in many species is the conjugation of activated xenobiotics to reduced glutathione (GSH) catalyzed by the glutathione-S-transferase (GST).
Emma E. Ramsay, Pierre J. Dilda
doaj +1 more source
Advanced Science, EarlyView.ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang +7 more
wiley +1 more source
A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes
, 2008 A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Monika Sivoňová +6 more
core
Advanced Science, EarlyView.This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan +10 more
wiley +1 more source
Protein S-Thiolation and oxidative stress in plants [PDF]
, 2002 The tripeptides glutathione (GSH; γglutamyl-cysteinyl-glycine) and homoglutathione (hGSH; γglutamyl-cysteinyl-β-alanine) are abundant cytosolic tripeptides in legumes.
Grundy, Nicholas Matthew
core
Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice
Advanced Science, EarlyView.This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang +9 more
wiley +1 more source
Increased serum homocysteine levels and glutathione-S-transferase activities in alcoholic patients attending de-addiction centre [PDF]
Саратовский научно-медицинский журнал, 2010 The purpose of this study was to investigate the effect of heavy alcohol consumption on serum Malondialdehyde, homocysteine status and glutathione-S -transferase (GST) activities in alcoholics consuming illicit liquor from lower socioeconomic background ...
Kulkarni S.R. +5 more
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