Results 91 to 100 of about 224,471 (305)

Targeting glutathione S-transferase M4 in Ewing sarcoma

Frontiers in Pediatrics, 2014
Ewing sarcoma is a malignant pediatric bone and soft tissue tumor. Although the 5-year survival rate of localized disease approaches 75%, the prognosis of metastatic and/or therapy-resistant disease remains dismal despite the wide use of aggressive ...
Rupeng eZhuo, kenneth ekosak, savita esankar, Elizabeth T Wiles, Ying eSun, Jianxing eZhang, Janet eAyello, Glenn ePrestwich, Paul eShami, Mitchell S Cairo, Stephen eLessnick, Wen eLuo   +11 more
doaj   +1 more source

Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]

, 2009
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang, Guang Wang, Jia Ma, Jun QI, Min-jie Wang, Qin Yin, Zhi-Xie Zhang   +6 more
core   +1 more source

Biochemical parameters of silver catfish (Rhamdia quelen) after transport with eugenol or essential oil of Lippia alba added to the water [PDF]

, 2017
The transport of live fish is a routine practice in aquaculture and constitutes a considerable source of stress to the animals. The addition of anesthetic to the water used for fish transport can prevent or mitigate the deleterious effects of transport ...
A. G. Becker, ALMROTH B.C., AZAMBUJA C.R., B. Baldisserotto, B. M. Heinzmann, BALDISSEROTTO B., BECKER A.G., BECKER A.G., BENOVIT S.C., BLENAU W., BRADFORD M.M., BUEGE J.A., C. C. Menezes, C. C. Zeppenfeld, C. Toni, COOKE S.J., CUNHA M.A., CUNHA M.A., DUBOIS M., ELLMAN G.L., ELLMAN G.L., GONÇALVES A.F.N., GOYAL A.K., HABIG W.H., HARROWER J.R., HUDETZ A.G., INOUE L.A.K.A., INOUE L.A.K.A., J. Salbego, LEUNG L.S., LINTERN M.C., LOWRY O.H., LÓPEZ M.D., MATÉS J.M., MAZZANTI L., MOMMSEN T.P., PANKHURST N.W., PARODI T.V., ROSS L.G., ROUBACH R., SALBEGO J., SALBEGO J., TONI C., UNGVARI Z., V. L. Loro, VALE T.G., VALE T.G., VILLARES JUNIOR G.A., YAN L.J., YONAR M.E., ZAHL I.H.   +50 more
core   +2 more sources

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Increased serum homocysteine levels and glutathione-S-transferase activities in alcoholic patients attending de-addiction centre [PDF]

Саратовский научно-медицинский журнал, 2010
The purpose of this study was to investigate the effect of heavy alcohol consumption on serum Malondialdehyde, homocysteine status and glutathione-S -transferase (GST) activities in alcoholics consuming illicit liquor from lower socioeconomic background ...
Kulkarni S.R., Ravindra К.Р., Dhume С., Rataboli P.V., Rodrigues E., Rodrigues E.E.   +5 more
doaj  

Inactivation of Anopheles gambiae Glutathione Transferase ε2 by Epiphyllocoumarin

Biochemistry Research International, 2016
Glutathione transferases (GSTs) are part of a major family of detoxifying enzymes that can catalyze the reductive dehydrochlorination of dichlorodiphenyltrichloroethane (DDT).
Patience Marimo, Rose Hayeshi, Stanley Mukanganyama   +2 more
doaj   +1 more source

Severe and prolonged myelosuppression during concomitant temozolomide and radiotherapy treatment in a patient with glioblastoma multiforme [PDF]

, 2015
Aims: We describe the case of a patient with glioblastoma (GBM) who developed severe and prolonged myelosuppression during concomitant daily temozolomide (TMZ) and radiotherapy (RT) treatment.
ALOE SPIRITI, Maria Antonietta, Carnevale, Alessia, Cox, Maria, DE SANCTIS, Vitaliana, Gentile, Giovanna, MAURIZI ENRICI, Riccardo, Minniti, Giuseppe, Porrini, ì Raffaele, Ruco, Luigi, Scaringi, Claudia, Simmaco, Maurizio, Tafuri, Agostino, Valeriani, Maurizio   +12 more
core   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni [PDF]

, 2000
A schistosome infection is initiated when the parasite penetrates the skin of a susceptible host. Relatively large quantities of protein are released by transforming cercariae compared to later larval stages.
Coulson, P.S., Harrop, R., Jennings, N., Moutford, A.P., Wilson, R.A.   +4 more
core   +1 more source