Results 271 to 280 of about 148,506 (307)
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Glutathione Transferases in the Bioactivation of Azathioprine
2014The prodrug azathioprine is primarily used for maintaining remission in inflammatory bowel disease, but approximately 30% of the patients suffer adverse side effects. The prodrug is activated by glutathione conjugation and release of 6-mercaptopurine, a reaction most efficiently catalyzed by glutathione transferase (GST) A2-2.
Olof, Modén, Bengt, Mannervik
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Glutathione transferases: Nomenclature
Biochemical Pharmacology, 1984W B, Jakoby, B, Ketterer, B, Mannervik
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Phylogenies of Glutathione Transferase Families
2005The best known glutathione transferase family, with its class-alpha, -mu, -pi, -omega, -sigma, -theta, and -zeta subdivisions, is only one of four, or perhaps five, ancient protein families that conjugate glutathione or use a glutathione intermediate: (1) the cytoplasmic family, (2) the mitochondrial (kappa) family, (3) the microsomal (MAPEG) family ...
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Interaction of haloacetonitriles with glutathione and glutathione-S-transferase
Biochemical Pharmacology, 1989E L, Lin, C W, Guion
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The Aedes aegypti glutathione transferase family
Insect Biochemistry and Molecular Biology, 2007Nongkran Lumjuan +2 more
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Microsomal glutathione transferase 1: mechanism and functional roles
Drug Metabolism Reviews, 2011Ralf Morgenstern, Katarina Johansson
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