Results 91 to 100 of about 7,638 (174)

Risk of bias summary of studies comparing glyburide to insulin.

, 2014
Risk of bias summary of studies comparing glyburide to insulin.
Muhammad Amin (169590), Naeti Suksomboon (524350), Nalinee Poolsup (524351)   +2 more
core   +1 more source

Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI

Journal of Lipid Research, 2012
To study the mechanisms of hepatic HDL formation, we investigated the roles of ABCA1, ABCG1, and SR-BI in nascent HDL formation in primary hepatocytes isolated from mice deficient in ABCA1, ABCG1, or SR-BI and from wild-type (WT) mice.
Ailing Ji, Joanne M. Wroblewski, Lei Cai, Maria C. de Beer, Nancy R. Webb, Deneys R. van der Westhuyzen   +5 more
doaj   +1 more source

Glyburide confers neuroprotection against age-related macular degeneration (AMD)

International audienceGlyburide, a sulfonylurea drug used to treat type 2 diabetes, boasts neuroprotective effects by targeting the sulfonylurea receptor 1 (SUR1) and associated ion channels in various cell types, including those in the central nervous ...
Torriglia, Alicia, Skondra, Dimitra, Picard, Emilie, Moir, John, Polak, Michel, Xie, Edward, Achiedo, Seiki, Daruich, Alejandra, Hyman, Max, J, Kaufmann, Gabriel, T, Crisanti, Patricia, Youale, Jenny, Behar-Cohen, Francine, Berdugo, Marianne   +13 more
core   +1 more source

Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers

, 2002
Background: Glyburide (INN, glibenclamide) is a second-generation sulfonylurea antidiabetic agent with high potency. We hypothesized that glyburide may be a substrate of cytochrome P450 2C9 (CYP2C9), an enzyme that has two low-activity amino acid ...
Kirchheiner, Julia, Bauer, S., Meisel, C., Roots, Ivar, Meineke, Ingolf, Brockmoeller, Juergen, Rohde, W.   +6 more
core   +1 more source

Pharmacodynamic effects of cimetidine and metronidazole on the blood glucose lowering effect of glyburide in rats

, 2006
The effects of the two imidazole derivatives (cimetidine and metronidazole) on the control of blood glucose level by Glyburide were determined in normal and hyperglycemic rats. Both imidazole derivatives insignificantly reduced the blood glucose lowering
CA Ezeagu, Ezeagu, CA, PO Udeogaranya, JM Okonta, Udeogaranya, PO, Okonta, JM   +5 more
core   +1 more source

Long-term safety and tolerability of saxagliptin add-on therapy in older patients (aged ≥65 years) with type 2 diabetes

Clinical Interventions in Aging, 2014
Nayyar Iqbal,1 Elsie Allen,1 Peter Öhman2 1Bristol-Myers Squibb, Princeton, NJ, USA; 2AstraZeneca, Wilmington, DE, USA Background: Treatment decisions for older patients with type 2 diabetes mellitus must balance glycemic control and adverse event
Iqbal N, Allen E, Öhman P
doaj  

Effect of exercise training and chronic glyburide treatment on glucose homeostasis in diabetic rats

, 1992
Exercise training and sulfonylurea treatment, either individually or in combination, were evaluated for their effects on plasma glucose concentrations, oral glucose tolerance, and glucose clearance in the perfused hindquarter of diabetic rats.
M. F. Hirshman, E. S. Horton, L. J. Goodyear, E. D. Horton   +3 more
core   +1 more source

Determinants of neonatal and maternal hypoglycemia in women with gestational diabetes treated with glyburide

, 2021
Le diabète gestationnel (DG), dont la prévalence était de 10,8% en 2016 en France, est associée à une morbidité maternelle et néonatale. Actuellement, le traitement de référence est l’insulinothérapie.
Bouchghoul, Hanane
core  

Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma

Nature Communications
Glioblastoma multiforme (GBM) remains a therapeutic challenge due to its aggressive nature and recurrence. This study establishes a radioresistant GBM cell model through repeated irradiation and observes a cellular senescence-like phenotype in these ...
Yuchuan Zhou, Liang Zeng, Linbo Cai, Wang Zheng, Xinglong Liu, Yuqi Xiao, Xiaoya Jin, Yang Bai, Mingyao Lai, Hainan Li, Hua Jiang, Songling Hu, Yan Pan, Jianghong Zhang, Chunlin Shao   +14 more
doaj   +1 more source

Poster Session 1

Pregnancy, Volume 2, Issue S2, September 2026.
wiley   +1 more source