Results 191 to 200 of about 145,105 (353)

Some preliminary data on the nature/structure of the PC-glycan of the major excretory-secretory product ofAcanthocheilonemaviteae (ES-62) [PDF]

, 1994
William Harnett, Mhairi J. Frame, Zurainee Mohamed Nor, M. Macdonald, Katrina M. Houston   +4 more
openalex   +1 more source

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

Chemistry – A European Journal, EarlyView.
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles. Immunization with a “diluted” amount of MUC1‐functionalized AuNPs is still capable of eliciting a strong immune response.
Mattia Ghirardello, Ana Guerreiro, Carmen Bretón, Ismael Compañón, Julio Zabalza, Vincenzo Mangini, Jesús M. Peregrina, Gonçalo J. L. Bernardes, Francisco Corzana   +8 more
wiley   +1 more source

Glycans and Chirality: Stereoselectivity at the Core of DC‐SIGN's Recognition. A Novel View of the Optimum Minimal Ligand Epitope

Chemistry – A European Journal, EarlyView.
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez, Reyes Núñez‐Franco, Pablo Valverde, Sandra Delgado, Ana Ardá, Jesús Jiménez‐Barbero, Gonzalo Jiménez‐Oses, F. Javier Cañada   +7 more
wiley   +1 more source

Synthesis studies on cell-surface glycans. Part 46 An efficient approach to a lactosamine synthon for the synthesis of I-type antigens.

, 1986
Yukishige Ito, Tomoya Ogawa
openalex   +2 more sources

Sulfated di‐, tri‐ and tetraantennary N‐glycans in human Tamm‐Horsfall glycoprotein [PDF]

, 1998
Johannes J.M. van Rooijen, Johannis P. Kamerling, Johannes F.G. Vliegenthart   +2 more
openalex   +1 more source

Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions

Chemistry – A European Journal, EarlyView.
Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker, Jan‐Simon Behnke, Leonhard H. Urner   +2 more
wiley   +1 more source

Synthetic studies on cell surface glycans. Part XX. Synthetic studies on nephritogenic glycosides. Synthesis of .BETA.-Glc-(1.RAR.6)-.ALPHA.-Glc-(1.RAR.6)-.ALPHA.-Glc-(1.RAR.Asn).

, 1983
Tomoya Ogawa, Seiichi Shibata, Satoru NAKABAYASHI   +2 more
openalex   +2 more sources

In the Biosynthesis of N‐Glycans in Connective Tissue of the Snail Lymnaea Stagnalis of Incorporation GlcNAc by β2GlcNAc‐transferase I is an essential prerequisite for the action of β2GlcNAc‐transferase II and β2Xyl‐transferase [PDF]

, 1995
Hans Mulder, Fabienne Dideberg, Harry Schachter, Bertina A. Spronk, Marijke de Jong‐Brink, Johannis P. Kamerling, Johannes F.G. Vliegenthart   +6 more
openalex   +1 more source

Improved C5‐Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2‐Deoxy‐2,3‐Didehydro‐N‐Acetyl Neuraminic Acid

ChemMedChem, EarlyView.
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan, Elisa G. Carvajal, Christopher W. Cairo   +2 more
wiley   +1 more source

Investigation of sample handling steps for accurate heparan sulphate disaccharide analysis using HPLC–MS

ELECTROPHORESIS, EarlyView.
Abstract Heparan sulphates (HSs), a specific class of glycosaminoglycans (GAGs), are important participants of cellular signalling. Analytical characterization of GAGs requires a complex sample preparation workflow. Although a detailed stability and recovery study is available for the chondroitin sulphate GAG class, the literature concerning HS is ...
Domonkos Pál, Gábor Tóth, Lilla Turiák   +2 more
wiley   +1 more source