Results 261 to 270 of about 144,829 (355)

CGE-LIF as a novel approach for the analysis of glycosphingolipid-derived glycans

, 2018
Charlotte Rossdam, Sarah A. Konze, Astrid Oberbeck, Erdmann Rapp, Rita Gerardy‐Schahn, Mark von Itzstein, Falk F. R. Buettner   +6 more
openalex   +1 more source

A Synthetic Glycan Microarray Enables Epitope Mapping of Plant Cell Wall Glycan-Directed Antibodies1

Plant Physiology, 2017
Colin Ruprecht, M. Bartetzko, Deborah Senf, Pietro Dallabernadina, I. Boos, M. Andersen, Toshihisa Kotake, J. Knox, M. Hahn, H. Mads, Clausen, F. Pfrengle   +11 more
semanticscholar   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Identification of a free-N-glycan with difucosylated type-1 lactosamine in cancerous tissue and its validation for cancer diagnosis by urinary testing. [PDF]

Sci Rep
Tanaka-Okamoto M, Hanzawa K, Yamamoto T, Ohkawa K, Yoshida KI, Takenaka S, Ohue M, Yamasaki T, Miyamoto Y.   +8 more
europepmc   +1 more source

Uncovering Sequence and Structural Characteristics of Fungal Expansin‐Related Proteins With Potential to Drive Substrate Targeting

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Expansins loosen plant cell wall networks through disrupting non‐covalent bonds between cellulose microfibrils and matrix polysaccharides. Whereas expansins were first discovered in plants, expansin‐related proteins have since been identified in bacteria and fungi.
Anna Pohto, Taru Koitto, Deepika Dahiya, Alessandra Castro, Elizaveta Sidorova, Martina Huusela, Scott E. Baker, Adrian Tsang, Emma Master   +8 more
wiley   +1 more source

The Impact of Methanol Concentration on Recombinant Protein Glycosylation in Pichia pastoris SuperMan5. [PDF]

Microb Biotechnol
Ohara A, Pengyue Z, Cao X, Donini R, Haslam SM, Polizzi KM.   +5 more
europepmc   +1 more source

Sensitive Electrochemical Aptamer Biosensor for Dynamic Cell Surface N-Glycan Evaluation Featuring Multivalent Recognition and Signal Amplification on a Dendrimer–Graphene Electrode Interface

, 2014
Xiaojiao Chen, Yangzhong Wang, Youyu Zhang, Zhuhai Chen, Yang Liu, Zhaolong Li, Jinghong Li   +6 more
openalex   +2 more sources

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini, Simona Saporiti, Crescenzo Coppa, Mara Rossi, Fabio Centola, Alessandro Arcovito   +5 more
wiley   +1 more source

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference. [PDF]

Nat Commun
Hvorecny KL, Interlandi G, Veth TS, Aprikian P, Manchenko A, Tchesnokova VL, Dickinson MS, Quispe JD, Riley NM, Klevit RE, Magala P, Sokurenko EV, Kollman JM.   +12 more
europepmc   +1 more source