Tissue-specific and sex-biased glycoproteomic landscape of Schistosoma mansoni. [PDF]
Chen X +13 more
europepmc +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
N-glycomics profiling reveals alteration of fucosylation in early acute ischemic stroke from mouse brain tissue to human serum. [PDF]
Wu Y +8 more
europepmc +1 more source
Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity [PDF]
Ciorba, Matthew A +9 more
core +1 more source
A Case for Anti‐IgE Vaccination
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
Selective clearance of monoclonal antibodies via the mannose receptor is dependent on glycan pairing. [PDF]
Baumeister J +8 more
europepmc +1 more source
Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard +10 more
wiley +1 more source
Exploratory analyses of cervicovaginal mucus O-glycan composition and microbiota profiles in unexplained infertility. [PDF]
Saqib S +6 more
europepmc +1 more source
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Revealing cancer glycome drivers using CRISPR activation screens. [PDF]
Decloquement M, Macauley MS.
europepmc +1 more source

