Results 221 to 230 of about 88,542 (309)

Glycosylation of the retina. [PDF]

Biochem Soc Trans
Swan J, Gagneux P.
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

An exploratory analysis of the associations of human milk oligosaccharides and N-/O-glycans with infectious and allergic outcomes in the first year of life: the Japanese Human Milk Study Cohort. [PDF]

Eur J Nutr
Tsujimori Y, Yamaguchi T, Toba Y, Fukudome H, Sakai F, Ueno HM, Higurashi S.   +6 more
europepmc   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza, Mathieu Fanuel, Hélène Rogniaux, David Ropartz   +3 more
wiley   +1 more source

Sugar-Coded Signals: Glycan-Based Biomarkers in Rheumatoid Arthritis. [PDF]

Mol Cell Proteomics
Hires M, Hroncekova S, Dujnič V, Solovicova V, Gajdosova VP, Jane E, Lorencova L, Bertok T, Vikartovska A, Datkova A, Kasak P, Kucera R, Tkac J.   +12 more
europepmc   +1 more source

Coregistration of Multimodal Imaging Mass Spectrometry and Optical Images of Tissue Sections at Single‐Cell Resolution

Surface and Interface Analysis, EarlyView.
ABSTRACT Accurate alignment of histopathological structures in optical images and imaging mass spectrometry (IMS) datasets is crucial for providing meaningful biological interpretation. Integrating IMS with optical or other imaging modalities remains challenging due to sample‐preparation constraints, mismatched spatial resolutions, and the need for ...
Ameh Orotomah, Rachel Pryce, Josianne Lefebvre, Raphaël Trouillon, Ludvik Martinu, Pierre Chaurand, Melissa K. Passarelli   +6 more
wiley   +1 more source

Acquisition of specific human respiratory tract binding by 2.3.4.4b H5N1 hemagglutinins requires multiple mutations. [PDF]

J Virol
Ríos Carrasco M, Guerreiro Cabana MF, Kovács E, Ducarne Z, Cleypool CGJ, Boons G-J, de Vries RP.   +6 more
europepmc   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

Sialidases and sialylated oligosaccharides in intestinal homeostasis and inflammation. [PDF]

Front Immunol
Abuhussein E, Singh DK, Yamaguchi Y, Orahovats CE, Cassidy OG, Tsuboi K, Huang L.   +6 more
europepmc   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source