Results 191 to 200 of about 4,938,448 (288)

Stage‐Dependent Prognostic Value of the Joint MASLD–NAFLD Fibrosis Score Phenotype Across the Cardiovascular–Kidney–Metabolic Syndrome Continuum: A Retrospective NHANES Cohort Analysis, 1999–2018

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The cardiovascular–kidney–metabolic (CKM) framework and metabolic dysfunction–associated steatotic liver disease (MASLD) describe a shared clinical continuum, but the prognostic value of joint fatty liver index (FLI)–NAFLD fibrosis score (NFS) phenotypes across CKM stages is uncertain.
Yi‐Fei Wang   +5 more
wiley   +1 more source

Sleep‐Autonomic Interactions in Parkinson's Disease and Multiple System Atrophy: A Comparative Study Using Structural Equation Modeling

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin   +5 more
wiley   +1 more source

Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan   +9 more
wiley   +1 more source

Diabetes‐Induced Dysregulation of Purinergic Signaling in the Bladder Mucosa: Accelerated ATP Hydrolysis and Impaired Adenosine Uptake Promote Underactive Bladder Phenotype

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Objective To explore molecular mechanisms underlying excessive extracellular adenosine (ADO) accumulation in the bladder lamina propria (LP) of mice with type 2 diabetes (T2D) induced by a high‐fat, high‐sucrose diet (HFHSD), conceivably leading to bladder underactivity.
Mahsa Borhani Peikani   +2 more
wiley   +1 more source

Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review

open access: yesNeurology and Clinical Neuroscience, EarlyView.
ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques   +4 more
wiley   +1 more source

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