Results 81 to 90 of about 1,279,661 (287)

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Dietary Glycemic Index, Glycemic Load, Cereal Fiber, and Plasma Adiponectin Concentration in Diabetic Men

, 2019
Objective - Adiponectin may improve insulin sensitivity, reduce inflammation, and ameliorate glycemic control. However, few studies have evaluated dietary predictors of plasma adiponectin levels, especially among subjects with type 2 diabetes.
Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600, Hu, F. B., Qi, L., Liu, S., Rifai, N.   +4 more
core   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

An Investigation of the Health Benefits of Honey as a Replacement For Sugar In the Diet [PDF]

, 2008
Sugar (primarily sucrose) has been a part of the daily diet for literally hundreds of years, but research is now suggesting that sugar intake can be detrimental to our health. In particular, excessive consumption of simple sugars with high glycemic index
Lynne Merran Chepulis, Chepulis, Lynne Merran   +1 more
core  

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Glycemic index and glycemic load in Brazilian Athletes's diets

Revista Brasileira de Nutrição Esportiva, 2019
Background: Glycemic Index (GI) and Glycemic Load (GL) have been used as tools for choosing diet as a health reference, and especially for athletes, with the purpose of improving physical performance.
Vania Letícia Souza Fernandes, Hellen Clair Garcez Nabuco, Ana Paula Muraro, Felipe Behrends Rodrigues, Fabrício César de Paula Ravagnani, Luiz Fabrizio Stoppiglia, Christianne de Faria Coelho Ravagnani   +6 more
doaj  

A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial

, 2007
BACKGROUND: Although the pathogenesis of acne is currently unknown, recent epidemiologic studies of non-Westernized populations suggest that dietary factors, including the glycemic load, may be involved. OBJECTIVE: The objective was to determine whether
Henna Makelainen (20007135), Robyn Smith (12576732), Neil Mann (12596211), George Varigos (20007138), Anna Braue (20007132)   +4 more
core  

Original Contribution Dietary Glycemic Index, Glycemic Load, and Risk of Cancer: A Prospective Cohort Study

, 2008
Previous studies have provided limited evidence for a harmful effect of high glycemic index and dietary glycemic load on cancer. The authors analyzed associations among glycemic index, glycemic load, and risk of cancer in women andmen in the National ...
A. Schatzkin, Michael F. Leitzmann, S. M. George, Schatzkin, A., Andrew Flood, Yikyung Park, Y. Park, Park, Y., A. F. Subar, Albert Hollenbeck, George, S. M., Mayne, S. T., Subar, A. F., Stephanie Materese George, Leitzmann, M. F., Hollenbeck, A., M. F. Leitzmann, S. T. Mayne, Flood, A., A. Flood, Susan T. Mayne, Arthur Schatzkin, A. Hollenbeck, Amy F. Subar   +23 more
core   +1 more source

Valorizing Food Waste (Banana Peel) Into an Edible Product: A Study on the Effect of Banana Peel Flour on the Physicochemical, Antioxidant, Textural, and Sensory Properties of Cookies

AgriFood: Journal of Agricultural Products for Food, EarlyView.
This study investigated the impact of banana peel flour (BPF) incorporation on cookies' nutritional, functional, physical, and antioxidant properties. The inclusion of BPF led to significant changes in the moisture, protein, crude fat, and ash contents of the developed cookies.
Km. Gudiya, Tariq Khan, Faizan Ahmad, Shubhangi Nigam   +3 more
wiley   +1 more source