Results 81 to 90 of about 26,291 (256)

Scientific Evidence for Different Options for GDM Screening and Management: Controversies and Review of the Literature. [PDF]

, 2017
Background. Gestational diabetes (GDM) affects up to 7% of pregnant women and is associated with several maternal and perinatal morbidities. International organizations suggest several different recommendations regarding how to screen and to manage GDM ...
Berghella, Vincenzo, Caissutti, Claudia
core   +3 more sources

Glycemic index, glycemic load, and risk of type 2 diabetes,, [PDF]

The American Journal of Clinical Nutrition, 2002
The possibility that high, long-term intake of carbohydrates that are rapidly absorbed as glucose may increase the risk of type 2 diabetes has been a long-standing controversy. Two main mechanisms have been hypothesized, one mediated by increases in insulin resistance and the other by pancreatic exhaustion as a result of the increased demand for ...
Walter, Willett, JoAnn, Manson, Simin, Liu   +2 more
openaire   +2 more sources

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca, Fioretto, Paola, Rossato, Marco, Vettor, Roberto, Zambon, Alberto   +4 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Correlation between quality and quantity of dietary carbohydrate and obesity in a group of women from Ahvaz

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: Obesity and being overweight are one of current nutritional disorders found in many developed and developing countries such as Iran, it seems that recently the role of carbohydrates in the formation of such illness has been ...
Farideh Shishehbor , Zahra Shamekhi , Majid Karandish , Seyed Mahmoud Latifi   +3 more
doaj  

Association of dietary glycemic and insulin index/load with odds of major depressive disorder: a case-control study

BMC Psychiatry
Background Dietary carbohydrate quality, reflected by glycemic index/load and insulin index/load, may influence brain function and mood through mechanisms such as glycemic fluctuations, oxidative stress, and inflammation.
Mahtab Karami Talandashti, Hossein Shahinfar, Mohammad Effatpanah, Jamileh Abolghasemi, Reyhaneh Morad Abbasi, Shima Jazayeri   +5 more
doaj   +1 more source

Mechanisms for the Increased Fatigability of the Lower Limb in People with Type 2 Diabetes [PDF]

, 2018
Fatiguing exercise is the basis of exercise training and a cornerstone of management of type 2 diabetes mellitus (T2D), however, little is known about the fatigability of limb muscles and the involved mechanisms in people with T2D.
Harkins, April, Harmer, Alison R, Hunter, Sandra K., Magill, Steven B., Senefeld, Jonathon   +4 more
core   +2 more sources

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source