Results 71 to 80 of about 1,279,661 (287)

Carbohydrates, Glycemic Index, and Glycemic Load in Relation to Bladder Cancer Risk

open access: yesFrontiers in Oncology, 2020
Objective: Epidemiologic studies investigating the association between dietary carbohydrates as well as glycemic index and glycemic load (markers of carbohydrate quality) and bladder cancer risk have yielded inconsistent results.
Hejia Zhu   +6 more
doaj   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu   +16 more
wiley   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

open access: yesAdvanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao   +11 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Glycemic index, glycemic load, and risk of type 2 diabetes,, [PDF]

open access: yesThe American Journal of Clinical Nutrition, 2002
The possibility that high, long-term intake of carbohydrates that are rapidly absorbed as glucose may increase the risk of type 2 diabetes has been a long-standing controversy. Two main mechanisms have been hypothesized, one mediated by increases in insulin resistance and the other by pancreatic exhaustion as a result of the increased demand for ...
Walter, Willett   +2 more
openaire   +2 more sources

Influência do índice glicêmico do alimento na palatabilidade e saciedade: um estudo com mulheres saudáveis e diabéticas [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-graduação em Ciência dos AlimentosNos últimos 20 anos têm-se intensificado os estudos sobre o Índice Glicêmico dos alimentos (IG), o qual tem sido ...
Batista, Sonia Maria de Medeiros
core  

Dietary Carbohydrate, Glycemic Index, and Glycemic Load in Relation to Risk of Colorectal Cancer in Women

open access: yes, 2019
Diets with a high glycemic index and glycemic load have been hypothesized to be implicated in the etiology of colorectal cancer owing to their potential to increase postprandial glucose and insulin levels.
Larsson, S. C.   +2 more
core   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

open access: yesAdvanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang   +11 more
wiley   +1 more source

Correlation between quality and quantity of dietary carbohydrate and obesity in a group of women from Ahvaz

open access: yesJournal of Fasa University of Medical Sciences, 2013
Background & Objective: Obesity and being overweight are one of current nutritional disorders found in many developed and developing countries such as Iran, it seems that recently the role of carbohydrates in the formation of such illness has been ...
Farideh Shishehbor   +3 more
doaj  

Association of dietary glycemic and insulin index/load with odds of major depressive disorder: a case-control study

open access: yesBMC Psychiatry
Background Dietary carbohydrate quality, reflected by glycemic index/load and insulin index/load, may influence brain function and mood through mechanisms such as glycemic fluctuations, oxidative stress, and inflammation.
Mahtab Karami Talandashti   +5 more
doaj   +1 more source

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