Results 61 to 70 of about 1,258,513 (286)

Diabetic Autonomic Imbalance and Glycemic Variability [PDF]

Journal of Diabetes Science and Technology, 2012
Diabetic autonomic neural imbalance is a severe complication of long-term diabetes patients and may progress to diabetic autonomic neuropathy (DAN). The prevalence of DAN is reported to be between 20 and 70%, depending on the studies. The pathogenesis of DAN remains unresolved.
openaire   +2 more sources

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Continuous glucose monitoring reveals glycemic variability and hypoglycemia after vertical sleeve gastrectomy in rats

Molecular Metabolism, 2020
Objective: Post–bariatric surgery hypoglycemia (PBH) is defined as the presence of neuroglycopenic symptoms accompanied by postprandial hypoglycemia in bariatric surgery patients.
Simon S. Evers, Ki-Suk Kim, Nadejda Bozadjieva, Alfor G. Lewis, Diana Farris, Matthew J. Sorensen, Youngsoo Kim, Steven E. Whitesall, Robert T. Kennedy, Daniel E. Michele, Randy J. Seeley, Darleen A. Sandoval   +11 more
doaj   +1 more source

Insulin Degludec Versus Insulin Glargine on Glycemic Variability in Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Frontiers in Endocrinology, 2022
Background/AimsCurrently, glycemic variability has more deleterious effects than sustained hyperglycemia and is closely associated with acute and chronic complications of diabetes.
Yunjiao Yang, Yunjiao Yang, Cong Long, Cong Long, Tongyi Li, Tongyi Li, Qiu Chen   +6 more
doaj   +1 more source

Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination? [PDF]

Frontiers in Microbiology, 2017
Following the 2009 H1N1 influenza virus pandemic, numerous studies identified the striking link between diabetes mellitus and influenza disease severity. Typically, influenza virus is a self-limiting infection but in individuals who have a pre-existing chronic illness, such as diabetes mellitus, severe influenza can develop. Here, we discuss the latest
Katina D. Hulme, Linda A. Gallo, Linda A. Gallo, Kirsty R. Short, Kirsty R. Short   +4 more
openaire   +6 more sources

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Association Between Long-Term HbA1c Variability and Functional Limitation in Individuals Aged Over 50 Years: A Retrospective Cohort Study

Frontiers in Endocrinology, 2022
BackgroundAs mean HbA1c provides incomplete information regarding glycemic variability, there has been considerable interest in the emerging association between glycemic variability and macrovascular events and with microvascular complications and ...
Di Shao, Shuang-Shuang Wang, Ji-Wei Sun, Ji-Wei Sun, Hai-Peng Wang, Qiang Sun   +5 more
doaj   +1 more source

Glycemic variability and outcome in critically ill

Indian Journal of Critical Care Medicine, 2014
Acute hyperglycemia, hypoglycemia and glycemic variability (GV) have been found to be the three principal domains of glycemic control, which can adversely affect patient outcome. GV may be the confounding factor in tight glycemic control trials in surgical and medical patient.This study was conducted to establish if there was any relationship between ...
Todi, Subhash, Bhattacharya, Mahuya
openaire   +3 more sources

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Postoperative glycemic variability in diabetic and non diabetic patients [PDF]

, 2011
Objectives: Glycemic variability increases oxidative stress and may trigger the inflammation and coagulation cascades. Variability may be associated with increase morbidity and mortality in ICU patients.
O\u27Malley, RN, Kathleen, Yeo, MD, Charles J., Joseph, Jeffrey, Gratch, DO, David, Simpson, MEng, Peter, Mraovic, MD, Boris, Lessin, RN, Jennifer, Grunwald, MD, Zvi, Hipszer, MD, Brian, Gulino, MD, Angela   +9 more
core   +1 more source