Results 1 to 10 of about 10,324 (247)

Proteomic Investigation of Glyceraldehyde-Derived Intracellular AGEs and Their Potential Influence on Pancreatic Ductal Cells

open access: yesCells, 2021
Glyceraldehyde-derived advanced glycation end products (AGEs) play an important role in the pathogenesis of many diseases including cancer. Accumulation of intracellular AGEs could stimulate cancer induction and facilitate cancer progression.
Lakmini Senavirathna   +3 more
doaj   +3 more sources

Glyceraldehyde metabolism in mouse brain and the entry of blood‐borne glyceraldehyde into the brain

open access: yesJournal of Neurochemistry
Abstract D‐Glyceraldehyde, a reactive aldehyde metabolite of fructose and glucose, is neurotoxic in vitro by forming advanced glycation end products (AGEs) with neuronal proteins. In Alzheimer's disease brains, glyceraldehyde‐containing AGEs have been detected intracellularly and in extracellular plaques. However,
Bjørnar Hassel   +2 more
exaly   +3 more sources

Prebiotic Synthesis of Sugar and Molecular Dynamic Simulation of 2,3-Dihydroxypropanal Adsorption on Montmorillonite [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2022
This study initially investigated sugar production through a Formose Reaction (FR) using methanol as a solvent and an aerosil (fumed silica) as a catalyst.
Arash Vojood   +4 more
doaj   +1 more source

Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts

open access: yesMetabolites, 2022
Cardiovascular disease (CVD) is a lifestyle-related disease (LSRD) induced by the dysfunction and cell death of cardiomyocytes. Cardiac fibroblasts are activated and differentiate in response to specific signals, such as transforming growth factor-β ...
Takanobu Takata   +2 more
doaj   +1 more source

Comparison of selectivity of ethylene glycol synthesis and glyceraldehyde biomolecule through Formose reaction in water and methanol solvent [PDF]

open access: yesشیمی کاربردی روز, 2022
In the present paper, the Formose reaction to produce polyols in methanol solvent in the presence of an aerosil (fumed silica) catalyst is first investigated.
Arash Vojood   +4 more
doaj   +1 more source

Pyridoxamine and Aminoguanidine Attenuate the Abnormal Aggregation of β-Tubulin and Suppression of Neurite Outgrowth by Glyceraldehyde-Derived Toxic Advanced Glycation End-Products

open access: yesFrontiers in Pharmacology, 2022
Diabetes mellitus (DM) has been identified as a risk factor for the onset and progression of Alzheimer’s disease (AD). In our previous study, we demonstrated that glyceraldehyde (GA)-derived toxic advanced glycation end-products (toxic AGEs, TAGE ...
Hayahide Ooi   +4 more
doaj   +1 more source

Photoelectrochemical Selective Oxidation of Glycerol to Glyceraldehyde with Bi-Based Metal–Organic-Framework-Decorated WO3 Photoanode

open access: yesNanomaterials, 2023
The conversion of glycerol to high-value-added products via photoelectrochemical (PEC) oxidation has emerged as a promising approach for utilizing a sustainable and clean energy source with environmental and economic benefits.
Yoonsung Jung   +9 more
doaj   +1 more source

Glyceraldehyde as an Efficient Chemical Crosslinker Agent for the Formation of Chitosan Hydrogels

open access: yesGels, 2021
The rheological changes that occur during the chemical gelation of semidilute solutions of chitosan in the presence of the low-toxicity agent glyceraldehyde (GCA) are presented and discussed in detail.
Pierre Carmona   +4 more
doaj   +1 more source

Glyceraldehyde-derived advanced glycation end-products having pyrrolopyridinium-based crosslinks

open access: yesBiochemistry and Biophysics Reports, 2021
Reducing sugars and reactive aldehydes, such as glyceraldehyde, non-enzymatically react with amino or guanidino groups of proteins to form advanced glycation end-products (AGEs) by the Maillard reaction that involves Schiff base formation followed by ...
Tomoaki Shigeta   +2 more
doaj   +1 more source

Glyceraldehyde-3-phosphate dehydrogenase [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981
Abstract Conflicting experimental evidence of the pathway of catalysis for the enzyme from rabbit, pig and lobster muscle tissues is reviewed. Transient kinetic studies with the enzyme from rabbit muscle are presented. The results are shown to be consistent with the double-displacement mechanism of catalysis originally proposed by ...
K, Dalziel, N V, McFerran, A J, Wonacott
openaire   +2 more sources

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