Results 91 to 100 of about 10,324 (247)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Selective Oxidation of Glycerol to Glyceraldehyde over Novel Monometallic Platinum Catalysts

Several novel monometallic platinum catalysts supported on metal oxides (Al2O3, Y2O3, γ-Al2O3, Lu2O3, ZrO2-Y2O3 TiO2, SiO2, γ-AlO(OH)) and activated carbon (C) were synthesized by extractive-pyrolytic method and tested in glycerol oxidation processes ...
Dubencovs, Konstantīns, Sīle, Elīna, Čornaja, Svetlana, Kampars, Valdis, Serga, V., Cvetkovs, A., Kuļikova, L.   +6 more
core   +1 more source

Nucleotide degradation and ribose salvage in yeast

Molecular Systems Biology, 2013
Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway.
Yi‐Fan Xu, Fabien Létisse, Farnaz Absalan, Wenyun Lu, Ekaterina Kuznetsova, Greg Brown, Amy A Caudy, Alexander F Yakunin, James R Broach, Joshua D Rabinowitz   +9 more
doaj   +1 more source

GLYCERALDEHYDE METABOLISM IN RHODOTORULA.

, 1967
GLYCERALDEHYDE METABOLISM IN ...
JOHN ALFRED. WATSON (7957619)
core  

glyceraldehyde 3‐phosphate dehydrogenase: Enzyme kinetics, high‐resolution crystal structure, and plasminogen binding

, 2020
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an evolutionarily conserved essential enzyme in the glycolytic pathway. GAPDH is also involved in a wide spectrum of non-catalytic cellular 'moonlighting' functions.
Joseph R. Gould, Debasish Chattopadhyay, Katherine L. Hayden, Glen C. Ulett, Hayden, Katherine L, Senkovich, Olga, Motamed, Rachael, Ulett, Glen C, Olga Senkovich, Todd J. Green, Norbert Schormann, Juan Campos, Chattopadhyay, Debasish, Schormann, Norbert, Campos, Juan, Green, Todd J, Rachael Motamed, Surajit Banerjee, Gould, Joseph R, Banerjee, Surajit   +19 more
core   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

The metabolism of d-glyceraldehyde by the lens [PDF]

Biochemical Journal, 1969
1. The metabolism of d-glyceraldehyde by the lens was examined. 2. When low concentrations of d-[U−14C]glyceraldehyde were incubated with lens extracts there was no incorporation of the label into protein; more than two-thirds of the labelled metabolites consisted of glyceric acid and glycerol, their relative proportions depending on the species ...
openaire   +2 more sources

Optical activity of D-glyceraldehyde in aqueous solutions

, 1984
In dilute aqueous solutions, D-glyceraldehyde exists both in the free and hydrated monomeric forms; the equilibrium between them depends on the temperature. The specific rotation of the equilibrium mixture was measured polarimetrically in the temperature
Michal Fedoroňko
core   +1 more source