Results 321 to 330 of about 1,056,672 (415)

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Crystal Structure of an Aldo-keto Reductase MGG_00097 from Magnaporthe grisea. [PDF]

Plant Pathol J
Huang X, Jiang H, Lin Y, Li X, Bi C, Qi S, Tang D, Wang Z, Lin S.   +8 more
europepmc   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol. [PDF]

Sci Rep
Li Q, Niu C, Guo J, Chen G, Li J, Sun L, Li W, Li T.   +7 more
europepmc   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

Advanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu, Yuanyuan Zhu, Guangjue Tang, Ming Shan, Puwen Tan, Ying Yi, Xiyuan Zhang, Man Liu, Xinyu Li, Le Wu, Jia Chen, Hailong Zheng, Yan Huang, Zhuan Li, Xiaobo Li, Dong Wang   +15 more
wiley   +1 more source

Edible Film Based on Rambutan Seed (<i>Nephelium lappaceum</i>) Starch: An Alternative Biodegradable Food Packaging. [PDF]

Prev Nutr Food Sci
Rahmawati S, Yassaroh Y, Alda A, Afadil A, Hamzah B, Abram PH.   +5 more
europepmc   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Insights from aquaporin structures into drug-resistant sleeping sickness

Matusevicius M, Corey RA, Gragera M, Yamashita K, Sprenger T, Ungogo MA, Blaza JN, Castro-Hartmann P, Chirgadze DY, Chaitanya Vedithi S, Afanasyev P, Melero R, Warshamanage R, Gusach A, Carazo JM, Carrington M, Blundell TL, Murshudov G, Stansfeld P, Sansom M, de Koning HP, Tate CG, Weyand SN.   +22 more
europepmc   +1 more source

Mechanistic Insights into Glycerol Oxidation to High-Value Chemicals via Metal-Based Catalysts. [PDF]

Molecules
Li J, Tu Y, He K, Chen C, Liang L, Ruan C, Zhang Q.   +6 more
europepmc   +1 more source