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Detectability of Glycine in Solar-type System Precursors [PDF]

open access: yes, 2014
Glycine (NH2CH2COOH) is the simplest amino acid relevant for life. Its detection in the interstellar medium is key to understand the formation mechanisms of pre-biotic molecules and their subsequent delivery onto planetary systems. Glycine has extensively been searched for toward hot molecular cores, although these studies did not yield any firm ...
Caselli, Paola   +3 more
arxiv   +3 more sources

A Search for Propylene Oxide and Glycine in Sagittarius B2 (LMH) and Orion [PDF]

open access: yesMon.Not.Roy.Astron.Soc.376:1201-1210,2007, 2007
We have used the Mopra Telescope to search for glycine and the simple chiral molecule propylene oxide in the Sgr B2 (LMH) and Orion KL, in the 3-mm band. We have not detected either species, but have been able to put sensitive upper limits on the abundances of both molecules. The 3-sigma upper limits derived for glycine conformer I are 3.7 x 10^{14} cm^
B. Fulton   +21 more
arxiv   +3 more sources

Chiral symmetry breaking via crystallization of the glycine and α-amino acid system: a mathematical model [PDF]

open access: yesPhys. Chem. Chem. Phys., 2011, 13, 12920-12934, 2011
We introduce and numerically solve a mathematical model of the experimentally established mechanisms responsible for the symmetry breaking transition observed in the chiral crystallization experiments reported by I. Weissbuch, L. Addadi, L. Leiserowitz and M. Lahav, J. Am. Chem. Soc. 110 (1988), 561-567.
Avetisov   +22 more
arxiv   +3 more sources

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells [PDF]

open access: yesCell Reports, 2014
Previous work has shown that some cancer cells are highly dependent on serine/glycine uptake for proliferation. Although serine and glycine can be interconverted and either might be used for nucleotide synthesis and one-carbon metabolism, we show that ...
Labuschagne, Christiaan F.   +4 more
core   +3 more sources

Assessing the causal association of glycine with risk of cardio-metabolic diseases [PDF]

open access: yesNature Communications, 2019
Circulating levels of glycine have previously been associated with lower incidence of coronary heart disease (CHD) and type 2 diabetes (T2D) but it remains uncertain if glycine plays an aetiological role.
Burgess, S   +22 more
core   +2 more sources

A synthetic BBB-permeable tripeptide GCF confers neuroprotection by increasing glycine in the ischemic brain

open access: yesFrontiers in Pharmacology, 2022
Background: We and others have previously demonstrated that glycine is neuroprotective in cerebral ischemia-reperfusion injury. But glycine has low permeability to the blood–brain barrier (BBB).
Juan Chen   +15 more
doaj   +1 more source

Subgingival air-polishing treatment in patients with aggressive periodontitis [PDF]

open access: yesVojnosanitetski Pregled, 2021
Background/Aim. Periodontal tissue maintenance therapy is an important phase of the overall periodontal disease therapy. This paper aims to determine subgingival air-polishing efficacy with glycine powder in putative paropathogens reduction, plaque index,
Trtić Nataša   +8 more
doaj   +1 more source

Synthesis and spectral characterizations of vanadyl(ii) and chromium(iii) mixed ligand complexes containing metformin drug and glycine amino acid

open access: yesOpen Chemistry, 2021
Metformin is one of the most effective drugs for the treatment of type II diabetes. Two new mixed ligand complexes of vanadyl(ii) and chromium(iii) ions with the general formula [VOL1L2]SO4 and [CrL1L2(Cl)2]Cl, respectively, where L1 is the metformin and
Aljazzar Samar O.
doaj   +1 more source

QSAR Relationships The Changes in the Ratio of Electrons to the Natural Charge of Atoms in the Complexes of Glycine and Alanine Amino Acids with Intermediates [PDF]

open access: yesInternational Journal of New Chemistry, 2017
In this paper, the quantum chemistry calculations related to the structural parameter of the three anions and the resulting complexes with glycine and alanine have been performed.
Hamideh Shahzad
doaj   +1 more source

Glycine neurotransmission: Its role in development

open access: yesFrontiers in Neuroscience, 2022
The accurate function of the central nervous system (CNS) depends of the consonance of multiple genetic programs and external signals during the ontogenesis.
Rocío Salceda
doaj   +1 more source

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