Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure
Chemical reactions of amino acids induced by discharge plasma are important for understanding the mechanism of biological effects of discharge plasma in biomedical applications.
Yui Hayashi +4 more
doaj +1 more source
Dışsal Glisin Uygulamasıyla Allium cepa L.'da Tuz Teşvikli Stresin Hafifletilmesi
Bu çalışmada, tuzluluğa maruz bırakılan Allium cepa L. tohumlarındaki fizyolojik parametreler olarak tohum çimlenmesi, radikula uzunluğu, radikula sayısı, taze ağırlık ve sitogenetik parametreler olarak mitotik aktivite, kromozomal anormallikler ve ...
Dilek ÇAVUŞOĞLU
doaj +1 more source
Today, Ukraine is ranked first in Europe in terms of cerebrovascular morbidity and mortality from stroke. Therefore, the creation of new drugs for the treatment of these pathologies is an urgent task of modern pharmacy. For that reason, the creation of a
L. I. Kucherenko +3 more
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THE INFLUENCE OF EXOGENOUS GLYCINE ON GROWTH AND INTENSITY OF CYANOBACTERIA Spirulina рlatensis (Gom.) Geitl PHOTOSYNTHETIC PROCESSES [PDF]
The aim of the work was to study the impact of glycine on Spirulina growth and photosynthetic processes intensity. For research the culture of Spirulina platensis (Gom.) Geitl cyanobacterium strain LGU — 603 from collection of Kholodny Institute of ...
A. V. Kotinskyi +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
QSAR Relationships The Changes in the Ratio of Electrons to the Natural Charge of Atoms in the Complexes of Glycine and Alanine Amino Acids with Intermediates [PDF]
In this paper, the quantum chemistry calculations related to the structural parameter of the three anions and the resulting complexes with glycine and alanine have been performed.
Hamideh Shahzad
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