Results 111 to 120 of about 969,294 (383)
A nutrient solution experiment was performed using sand culture to evaluate the effects of different glycine levels on the growth and nutrient uptake of coriander (Coriandrum sativum L.).
Nikta Mohammadipour, M. Souri
semanticscholar +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Glycine supplementation extends lifespan of male and female mice
Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan of Fischer 344 rats.
Richard A. Miller+16 more
semanticscholar +1 more source
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
Tuning the Flexibility of Glycine-Serine Linkers To Allow Rational Design of Multidomain Proteins
Flexible polypeptide linkers composed of glycine and serine are important components of engineered multidomain proteins. We have previously shown that the conformational properties of Gly-Gly-Ser repeat linkers can be quantitatively understood by ...
M. van Rosmalen, Mike D. Krom, M. Merkx
semanticscholar +1 more source
The activation mechanism of alpha 1 homomeric glycine receptors [PDF]
The glycine receptor mediates fast synaptic inhibition in the spinal cord and brainstem. Its activation mechanism is not known, despite the physiological importance of this receptor and the fact that it can serve as a prototype for other homopentameric ...
Beato, M+3 more
core
The Functional DRD3 Ser9Gly Polymorphism (rs6280) Is Pleiotropic, Affecting Reward as Well as Movement [PDF]
Abnormalities of motivation and behavior in the context of reward are a fundamental component of addiction and mood disorders. Here we test the effect of a functional missense mutation in the dopamine 3 receptor (DRD3) gene (ser9gly, rs6280) on reward ...
A Agrawal+90 more
core +3 more sources
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
Interaural time difference processing in the mammalian medial superior olive [PDF]
The dominant cue for localization of low-frequency sounds are microsecond differences in the time-of-arrival of sounds at the two ears [interaural time difference (ITD)].
Behrend, Oliver+3 more
core +1 more source
Maillard Type Reaction for Electroless Copper Plating onto Ceramic Nanoparticles
This work presents the manufacturing of copper‐plated ceramic nanoparticles in an environmentally friendly way. Supported by organic functionalizations with pectin an electroless plating step can be performed. Sustainable reagents like xylose, and several amino acids are used for the reduction process.
Lukas Mielewczyk+8 more
wiley +1 more source