Results 191 to 200 of about 622,510 (345)

High‐Performance Black Phosphorus/Graphitic Carbon Nitride Heterostructure‐Based Wearable Sensor for Real‐time Sweat Glucose Monitoring

open access: yesAdvanced Materials Technologies, EarlyView.
This work introduces a BP‐gCN heterostructure‐based wearable glucose sensor designed for continuous, non‐invasive glucose monitoring. By enhancing electrochemical glucose oxidation, the sensor exhibits improved sensitivity and stability. The integration of DFT calculations and experimental results demonstrates the superior electrocatalytic performance ...
Ecem Ezgi Özkahraman   +9 more
wiley   +1 more source

One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression. [PDF]

open access: yesCancer Res Commun
Zirpoli S   +7 more
europepmc   +1 more source

Asymmetric Strategies for the Synthesis of Enantiopure α‐/β‐/γ‐Thio‐Carboxylic Acids Bearing a Stereocentre at CS Bond

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley   +1 more source

Tunable Preparation of α‐Aminoacyl Fluorides and α‐Fluoroamides via Base‐Induced Cascade Multiple‐Cleavage Processes from Bromodifluorohydrin Reagents and Amines

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A mild and versatile strategy enabling the divergent synthesis of α‐fluoroamides and α‐aminoacyl fluorides from 2‐bromo‐2,2‐difluoro alcohols and amines is developed. The reaction shows broad scope and operational simplicity. Mechanistic and density functional theory studies support the formation of a putative gem‐difluoroepoxide intermediate ...
Giulia De Santis   +8 more
wiley   +1 more source

Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Gregory S. Ducker   +10 more
semanticscholar   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

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