Results 251 to 260 of about 1,006,170 (352)

Molecular basis of EWS interdomain self-association and its role in condensate formation. [PDF]

Protein Sci
Sohn EJ, Sojitra KA, Rodrigues L, Xu X, Frost B, Mittal J, Libich DS.   +6 more
europepmc   +1 more source

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

Advanced Science, EarlyView.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan, Yuting Zhu, Ben Tang, Yaru Xie, Mingcun Hu, Hua Su, Youhua Liu, Chun Zhang   +7 more
wiley   +1 more source

Rootstock-specific bacterial microbiome and metabolome remodeling enhances glycine substitution efficacy for ammonium nitrate in watermelon. [PDF]

Front Plant Sci
Chen Z, Yao T, Bao X, Wang Y, Qiao S, Tan L, Shi H, Chen X, Ding M.   +8 more
europepmc   +1 more source

METABOLIC STUDIES IN PATIENTS WITH CANCER OF THE GASTRO-INTESTINAL TRACT. XII—THE GLYCINE TOLERANCE TEST IN PATIENTS WITH GASTRIC CANCER*

, 1943
Irving M. Ariel, F.Harriman Jones, George T. Pack, C. P. Rhoads   +3 more
openalex   +2 more sources

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Recent Developments in Azomethine Ylide-Initiated Double Cycloadditions. [PDF]

Molecules
Zhou T, Zhang X, Sheng YJ, Zhan D, Zhang W.   +4 more
europepmc   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

Amino acid dysregulation in cerebrospinal fluid of stroke patients serving as diagnostic biomarkers in post-neurosurgical bacterial meningitis. [PDF]

Sci Rep
Chen W, Chen Y, Liu B, Ding L, Wang C, Cheng H, Ye L.   +6 more
europepmc   +1 more source

Motility of Bovine Spermatozoa Stored at 5° C. when Extended in Mixtures of Yolk-Citrate, Yolk-Glycine, Whole Milk, Skimmilk, and Glycerol

, 1958
J.L. Albright, Martin Ehlers, R.E. Erb
openalex   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source