Results 11 to 20 of about 3,903 (108)

Activities of Hepatic Cytosolic and Mitochondrial Forms of Serine Hydroxymethyltransferase and Hepatic Glycine Concentration Are Affected by Vitamin B-6 Intake in Rats [PDF]

The Journal of Nutrition, 2005
Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP)-dependent enzyme that exists as cytosolic and mitochondrial isozymes that catalyze the reversible interconversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methyleneTHF.
Jennifer B, Scheer, Amy D, Mackey, Jesse F, Gregory   +2 more
openaire   +2 more sources

A comparative study of the kinetics and stereochemistry of the serine hydroxymethyltransferase- and tryptophan synthase-catalysed exchange of the pro-2R and pro-2S protons of glycine [PDF]

Biochemical Journal, 1991
The stereospecificity of the serine hydroxymethyltransferase (EC 2.1.2.1)- and tryptophan synthase (EC 4.2.1.20)- catalysed exchange of the pro-2R and pro-2S alpha-protons of glycine was investigated by using 13C n.m.r. The exchange process is described in terms of a minimal four-step mechanism, and a method for analysing the exchange process by ...
J P, Malthouse, J J, Milne, L S, Gariani
openaire   +2 more sources

The role of serine hydroxymethyltransferase 1 (CHSHMT1) in the regulation of the key osmolyte glycine in the estuarine Hong Kong oyster Crassostrea hongkongensis under osmotic stress

Aquaculture Reports
The estuarine Crassostrea hongkongensis is the major cultured oyster species in the South China, and mass mortality induced by hyper-salinity has heavily damaged the oyster farming, especially during dry season. To benefit the genetic improvement of hyper-salinity tolerance, three genes related to the intracellular concentration of glycine (Gly) that ...
Chenyang Yue, Xinyu Song, Salifu Ibrahim, Wengang Lü, Yuewen Deng, Qi Li   +5 more
openaire   +2 more sources

Amino acid metabolism of the thermophilic acetogen Thermacetogenium phaeum. [PDF]

PLoS One
Cai Y, Marquardt A, Schleheck D, Müller N.   +3 more
europepmc   +1 more source

Hypoxia facilitates triple-negative breast cancer stem cells enrichment and stemness maintenance through oxidized ataxia telangiectasia mutated-induced one-carbon metabolism. [PDF]

World J Stem Cells
Yang D, Ou YL, Wang SH, Jin HJ, Chen SH, Han R, Zhang H.   +6 more
europepmc   +1 more source

The "serine code" of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy. [PDF]

Front Immunol
Su P, Yang Y, Zheng H.
europepmc   +1 more source

Glutamate potentiates susceptibility of P. aeruginosa clinical isolates to gentamycin: a new adjuvant hope for an old antibiotic. [PDF]

Front Microbiol
Nageeb WM, Hetta HF, Frampton D, Saunders NJ.   +3 more
europepmc   +1 more source

Metabolic engineering of Yarrowia lipolytica targeting bottlenecks to boost D-Pantothenic acid biosynthesis. [PDF]

Bioresour Bioprocess
Li XK, Zhang N, Li HP, Huang ZY, Niu GY, Sun CY, Xu JH.   +6 more
europepmc   +1 more source

Synergistic mitochondrial impairment by endogenously elevated cyanide and hydrogen sulfide in Down syndrome; commentary on: Cyanide overproduction impairs cellular bioenergetics in Down syndrome. [PDF]

Neurotherapeutics
Pieper AA, Paul BD.
europepmc   +1 more source

Molecular evolution of the Wood-Ljungdahl pathway and the reductive glycine pathway in <i>Desulfobacterota</i>. [PDF]

Front Microbiol
Wakashima T, Kume K, Chiba Y.
europepmc   +1 more source