Results 131 to 140 of about 258,627 (303)
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Asymmetric gating of a human hetero-pentameric glycine receptor. [PDF]
Nat Commun, 2023 Liu X, Wang W.
europepmc +1 more source
Modulação das funções do sistema glutamatérgico pelo receptor serotoninérgico 5-HT1A da substância cinzenta periaquedutal dorsal no comportamento defensivo de ratos [PDF]
, 2008 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Vários estudos têm caracterizado o envolvimento da substância cinzenta periaquedutal dorsal (SCPd) nas respostas ...
Moraes, Cladis Loren Kiefer
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Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
Advanced Science, EarlyView.This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
Injeção de glicina na substância cinzenta periaquedutal dorsal facilita ou inibe a nocicepção dependendo do contexto nociceptivo [PDF]
, 2009 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.A Substância Cinzenta Periaqueductal dorsal (SCPd) é reconhecida como uma estrutura do sistema nervoso central (SNC ...
Martins, Maria Alcina
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Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
The persistence and genetic support of genes encoding antibiotic resistance in oral bacteria.
, 2005 Antibiotic-resistant bacteria present a serious public health threat and studies investigating the prevalence of antibiotic-resistant bacteria and the genes encoding for antibiotic resistance (GEAR) are essential.
Lancaster, Holli Louise, Lancaster, H.L.
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Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Advanced Science, EarlyView.This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
, 2008 Soybean (Glycine max L. Merr.) resistance to populations (HgType) of _Heterodera glycines I._, the soybean cyst nematode (SCN), requires a functional allele at rhg1. An apoptosis-like response in the giant cells formed around the nematode results 24-48 h
Lightfoot, David A. +7 more
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