Results 171 to 180 of about 175,730 (291)

Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses. [PDF]

Elife
Camuso S, Vella Y, Youjil Abadi S, Mille C, Brône B, Specht CG.   +5 more
europepmc   +1 more source

A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors. [PDF]

Biomolecules, 2020
Sheipouri D, Gallagher CI, Shimmon S, Rawling T, Vandenberg RJ.   +4 more
europepmc   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

Advanced Science, EarlyView.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang, Weisong Liu, Hao Su, Huijuan Cui, Yuanming Wang, Zhiguang Zhu, Chun You, Lingling Zhang   +7 more
wiley   +1 more source

Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist. [PDF]

Sci Adv
Gibbs E, Feddersen B, Kindig KJ, Seiferth D, Biggin PC, Chakrapani S.   +5 more
europepmc   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Excitatory glycine receptors control ventral hippocampus synaptic plasticity and anxiety-related behaviors. [PDF]

Proc Natl Acad Sci U S A
Pizzamiglio L, Morice E, Cardoso C, Bossi S, Mailhes-Hamon C, Heimendahl MV, Girardeau G, Paoletti P.   +7 more
europepmc   +1 more source

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source

Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide. [PDF]

Sci Rep
Lara CO, Burgos CF, Fariña-Oliva K, Marileo AM, Martín VPS, Flaig D, Soto-Ortega P, Contreras OV, Sazo A, Gaete-Riquelme K, Corradi J, Muñoz-Montesino C, Fuentealba J, Castro PA, Aguayo LG, Bouzat C, Moraga-Cid G, Yévenes GE.   +17 more
europepmc   +1 more source

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

Advanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu, Yifan Zhang, Haolin Li, Shengyu Zhao, Xiaoran Dai, Qili Xu, Mintian Fei, Chun Li, Zhihui Zou, Baojun Wang, Li Zhang, Hui Wang, Ligang Zhang, Chaozhao Liang   +13 more
wiley   +1 more source

GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus. [PDF]

J Neurosci
Hurley EP, Mukherjee B, Fang LZ, Barnes JR, Barron JC, Nafar F, Hirasawa M, Parsons MP.   +7 more
europepmc   +1 more source