Results 1 to 10 of about 337,150 (208)

Glycogen and its metabolism: some new developments and old themes [PDF]

Biochemical Journal, 2012
Glycogen is a branched polymer of glucose that acts as a store of energy in times of nutritional sufficiency for utilization in times of need. Its metabolism has been the subject of extensive investigation and much is known about its regulation by ...
Depaoli-Roach, Anna A., Hurley, Thomas D., Roach, Peter J., Tagliabracci, Vincent S.   +3 more
exaly   +3 more sources

Postprandial Glycogen Content Is Increased in the Hepatocytes of Human and Rat Cirrhotic Liver

Cells, 2021
Chronic hepatitises of various etiologies are widespread liver diseases in humans. Their final stage, liver cirrhosis (LC), is considered to be one of the main causes of hepatocellular carcinoma (HCC). About 80–90% of all HCC cases develop in LC patients,
Natalia N. Bezborodkina, Sergey V. Okovityi, Boris N. Kudryavtsev   +2 more
doaj   +1 more source

Role of Astrocytes in the Pathophysiology of Lafora Disease and Other Glycogen Storage Disorders

Cells, 2023
Lafora disease is a rare disorder caused by loss of function mutations in either the EPM2A or NHLRC1 gene. The initial symptoms of this condition are most commonly epileptic seizures, but the disease progresses rapidly with dementia, neuropsychiatric ...
Jordi Duran
doaj   +1 more source

Ketotic hypoglycemia in patients with Down syndrome

JIMD Reports, 2021
Background Ketotic hypoglycemia (KH) without an identifiable underlying metabolic or hormonal disease is historically named idiopathic KH. The prevalence is unknown, but idiopathic KH is considered the most frequent cause of hypoglycemia beyond the ...
Danielle Drachmann, Austin Carrigg, David A. Weinstein, Jacob Sten Petersen, Henrik Thybo Christesen   +4 more
doaj   +1 more source

Cooling of male rat skeletal muscle during endurance‐like contraction attenuates contraction‐induced PGC‐1α mRNA expression

Physiological Reports, 2023
This study aimed to determine effects of cooling on contraction‐induced peroxisome proliferator‐activated receptor γ coactivator‐1α (PGC‐1α) and vascular endothelial growth factor (VEGF) gene expression, phosphorylations of its related protein kinases ...
Daisuke Hoshino, Ryota Wada, Yutaro Mori, Reo Takeda, Yudai Nonaka, Ryotaro Kano, Ryo Takagi, Yutaka Kano   +7 more
doaj   +1 more source

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]

, 2020
Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran, Glamuzina, Emma, Hedberg-Oldfors, Carola, Hernandez-Lain, Aurelio, Kornblum, Cornelia, Oldfors, Anders, Roach, Peter, Sandstedt, Joakim, Tasca, Giorgio, Thomsen, Christer, Visuttijai, Kittichate   +10 more
core   +1 more source

Does the Nutritional Composition of Dairy Milk Based Recovery Beverages Influence Post-exercise Gastrointestinal and Immune Status, and Subsequent Markers of Recovery Optimisation in Response to High Intensity Interval Exercise?

Frontiers in Nutrition, 2021
This study aimed to determine the effects of flavored dairy milk based recovery beverages of different nutrition compositions on markers of gastrointestinal and immune status, and subsequent recovery optimisation markers.
Isabella Russo, Paul A. Della Gatta, Andrew Garnham, Judi Porter, Judi Porter, Louise M. Burke, Ricardo J. S. Costa   +6 more
doaj   +1 more source

Comprehensive Analysis of Differentially Expressed mRNA, Non-coding RNA, and Their Competitive Endogenous RNA Network of Pacific Oyster Crassostrea gigas With Different Glycogen Content Between Different Environments

Frontiers in Marine Science, 2021
Glycogen content is a quantitative trait, its phenotype differences are found between individual oysters due to genetic effects and environmental factors which were including food, water temperature, salinity, and so on.
Xue Wang, Weijun Wang, Zan Li, Guohua Sun, Tao Xu, Xiaohui Xu, Yanwei Feng, Qihao Luo, Bin Li, Bin Li, Jianmin Yang, Jianmin Yang   +11 more
doaj   +1 more source

Manipulation of glycogen and sucrose synthesis increases photosynthetic productivity in cyanobacteria

Frontiers in Microbiology, 2023
Photosynthetic productivity is limited by low energy conversion efficiency in naturally evolved photosynthetic organisms, via multiple mechanisms that are not fully understood.
Michael Cantrell, Melissa Cano, Jacob Sebesta, Troy Paddock, Wei Xiong, Katherine J. Chou, Jianping Yu   +6 more
doaj   +1 more source

The Action of Recombinant Human Lysosomal α-Glucosidase (rhGAA) on Human Liver Glycogen: Pathway to Complete Degradation

International Journal of Translational Medicine, 2021
Glycogen is present in all tissues, but it is primarily stored in the liver and in muscle. As a branched chain carbohydrate, it is broken down by phosphorylase and debrancher enzymes, which are cytoplasmic.
Allen K. Murray
doaj   +1 more source