Results 21 to 30 of about 245,598 (258)
Natural and anthropogenic changes have been altering many environmental factors. These include the amount of solar radiation reaching the Earth’s surface. However, the effects of solar radiation on insect physiology have received little attention.
Chunchun Li +6 more
doaj +1 more source
Glycogen Synthase Kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells [PDF]
Nuclear myosin 1c (NM1) mediates RNA polymerase I (pol I) transcription activation and cell cycle progression by facilitating PCAF-mediated H3K9 acetylation, but the molecular mechanism by which NM1 is regulated remains unclear.
Laura Borgonovo-Brandter (573527) +44 more
core +1 more source
Following clinical indications, the laboratory diagnosis of the inherited metabolic myopathy, Pompe disease (PD), typically begins with demonstrating a reduction in acid alpha-glucosidase (GAA), the enzyme required for lysosomal glycogen degradation ...
Jennifer T. Saville, Maria Fuller
doaj +1 more source
Anti-Fatigue Activity of Aqueous Extracts of Sonchus arvensis L. in Exercise Trained Mice
Sonchus arvensis L. is a nutritious vegetable and herbal medicine that is consumed worldwide. The aim of this study was to evaluate the anti-fatigue effects and underlying effects of aqueous extract of Sonchus arvensis L. (SA).
Tian Yuan +9 more
doaj +1 more source
Use of neonicotinoid pesticides is now ubiquitous, and consequently non-targeted arthropods are exposed to their residues at sub-lethal doses. Exposure to these neurotoxins may be a major contributor to poor honey bee colony health.
Steven C. Cook
doaj +1 more source
Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. [PDF]
We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme muscle mass was developed during 138 generations of phenotype selection for high protein ...
Hammon Harald M. +53 more
core +2 more sources
Background There is an emerging theory suggesting that insulin, which is known to be the predominant postprandial anabolic hormone, is also a major regulator of mitochondrial oxidative phosphorylation in human skeletal muscle.
Gin Henri +4 more
doaj +1 more source
Glycogen, a critical nutrient in Crassostrea hongkongensis, exhibits essential biological properties, with its quantitative levels serving as a pivotal parameter for phenotypic selection and genetic improvement of superior oyster strains.
Lingxin Kong +6 more
doaj +1 more source
Deficiency of ASGR1 Alleviates Diet-Induced Systemic Insulin Resistance via Improved Hepatic Insulin Sensitivity [PDF]
Background Insulin resistance (IR) is the key pathological basis of many metabolic disorders. Lack of asialoglycoprotein receptor 1 (ASGR1) decreased the serum lipid levels and reduced the risk of coronary artery disease.
Xiaorui Yu +10 more
doaj +1 more source
Liver Glycogen Synthase in Rats with a Glycogen‐Storage Disorder [PDF]
1. A strain of rats with a genetically‐determined liver glycogen‐storage disorder (gsd/gsd) caused by a deficiency of liver phosphorylase kinase has a very high concentration of glycogen in the liver with a total glycogen synthase activity higher than in liver of fed normal animals, but only a small amount of the enzyme in the active form.
C, Watts, R S, Malthus
openaire +2 more sources

