Results 131 to 140 of about 260,438 (309)

Glycogen Granules Are Degraded by Non-Selective Autophagy in Nitrogen-Starved Komagataella phaffii

open access: yesCells
Autophagy was initially recognized as a bulk degradation process that randomly sequesters and degrades cytoplasmic material in lysosomes (vacuoles in yeast). In recent years, various types of selective autophagy have been discovered.
Nimna V. Wijewantha   +2 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

Glycogen and its metabolism: some new developments and old themes.

open access: yesBiochemical Journal, 2012
Glycogen is a branched polymer of glucose that acts as a store of energy in times of nutritional sufficiency for utilization in times of need. Its metabolism has been the subject of extensive investigation and much is known about its regulation by ...
P. Roach   +3 more
semanticscholar   +1 more source

The Impact of Phase Change Materials on Electricity Consumption in Prefabricated Temporary Houses

open access: yesEnergy Science &Engineering, EarlyView.
The effectiveness of phase change material (PCM) integration was evaluated over a 1‐month period under winter climate conditions, with electricity consumption serving as the primary metric. According to the results, the incorporation of PCMs led to a reduction in average electricity consumption by 16%, weighted average electricity consumption by 16.2%,
Fatih Selim Bayraktar, Ramazan Köse
wiley   +1 more source

Clinical and Genetic Aspects of Pompe Disease: A Review of Current Knowledge

open access: yesQuality in Sport
: Introduction:  Pompe disease is classified as a metabolic myopathy and is a glycogen storage disorder inherited in an autosomal recessive manner due to a mutation in the gene encoding the enzyme α-glucosidase.
Agata Konopka   +4 more
doaj   +1 more source

Tau‐targeting nanoparticles for treatment of Alzheimer's disease

open access: yesExploration, EarlyView.
Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar   +3 more
wiley   +1 more source

Balancing property optimization and constraint satisfaction for constrained multi-property molecular optimization [PDF]

open access: yesarXiv
Molecular optimization, which aims to discover improved molecules from a vast chemical search space, is a critical step in chemical development. Various artificial intelligence technologies have demonstrated high effectiveness and efficiency on molecular optimization tasks.
arxiv  

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

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