Results 171 to 180 of about 345,366 (342)
Advances in Enaminomaleimides Chemistry: Synthesis, Chemical Applications, and Perspectives
ChemistryEurope, EarlyView.Enaminomaleimides are versatile building blocks for the construction of functionalized heterocycles. Their unique nucleophilic character, contrasting with the classical electrophilic nature of maleimides, enables diverse synthetic applications, showing promising potential in both materials science and medicinal chemistry.
Adrián López‐Francés +5 more
wiley +1 more source
Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma
ChemMedChem, EarlyView.Pyrazolo[1,5‐α]pyrimidinone derivatives exhibit selective cytotoxicity towards glioblastoma (GBM) cells over noncancerous cells. Structure–activity relationship studies identifies a lead compound with significant cytotoxicity activity, inducing apoptosis and necrosis in GBM cells, without affecting noncancerous cells. This demonstrates the potential of
Kate Byrne +5 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters +5 more
wiley +1 more source
Streptozotocin induced hyperglycemia in the axolotl
Developmental Dynamics, EarlyView.Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source
Polysaccharide storage myopathy - the story so far [PDF]
, 2015 Annandale +45 more
core +1 more source
GLYCOGEN REDUCTION IN CHICK LIVER DURING PULLORUM DISEASE [PDF]
, 1958 J. A. Cameron +2 more
openalex +1 more source
Ecography, EarlyView.Risk assessments of invasive species present one of the most challenging applications of species distribution models (SDMs) due to the fundamental issues of distributional disequilibrium, niche changes, and truncation. Invasive species often occupy only a fraction of their potential environmental and geographic ranges, as their spatiotemporal dynamics ...
Erola Fenollosa +4 more
wiley +1 more source