Results 21 to 30 of about 361,476 (236)
Hepatology Communications, 2019 Mutations in the liver glycogen phosphorylase (Pygl) gene are associated with the diagnosis of glycogen storage disease type VI (GSD‐VI). To understand the pathogenesis of GSD‐VI, we generated a mouse model with Pygl deficiency (Pygl−/−).
Lane H. Wilson +8 more
doaj +1 more source
Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]
, 2020 Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S +6 more
core +1 more source
Glycogen metabolism and glycogen storage disorders [PDF]
Annals of Translational Medicine, 2018 Glucose is the main energy fuel for the human brain. Maintenance of glucose homeostasis is therefore, crucial to meet cellular energy demands in both - normal physiological states and during stress or increased demands. Glucose is stored as glycogen primarily in the liver and skeletal muscle with a small amount stored in the brain.
Shibani, Kanungo +3 more
openaire +2 more sources
Patologìâ, 2013 Cardiovascular pathology may be formed on the background of the heart morphogenesis disturbances during fetal development. There is a high prevalence of pathological pregnancy, intrauterine infections of different etiology, accompanied by dysfunction of ...
A. N. Lebedinets
doaj +1 more source
Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. [PDF]
, 2014 Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic ...
Bridges, Dave +12 more
core +2 more sources
A forage-only diet alters the metabolic response of horses in training [PDF]
, 2012 Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson +45 more
core +2 more sources
Sleep and Wake Affect Glycogen Content and Turnover at Perisynaptic Astrocytic Processes
Frontiers in Cellular Neuroscience, 2018 Astrocytic glycogen represents the only form of glucose storage in the brain, and one of the outcomes of its breakdown is the production of lactate that can be used by neurons as an alternative energetic substrate.
Michele Bellesi +5 more
doaj +1 more source
AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease [PDF]
, 2017 Pompe disease (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extensive glycogen storage and impaired autophagy.
Alvino, Filomena Grazia +13 more
core +1 more source
Microscopy Research and Technique, 2004 AbstractGlycogen autophagy, which includes the sequestration and degradation of cell glycogen in the autophagic vacuoles, is a selective process under conditions of demand for the massive hepatic production of glucose, as in the postnatal period. It represents a link between autophagy and glycogen metabolism. The formation of autophagic vacuoles in the
Kotoulas, O. B. +2 more
openaire +3 more sources
Changes of gangliosides and other lipids in skeletal muscle from rabbits with experimental dystrophy
Journal of Lipid Research, 1974 Comparison of the skeletal muscles from vitamin E-deficient and control rabbits showed that the muscles from the deficient animals had lower contents of protein and glycogen but more water and lipid.
I. Albarracín, F.E. Lassaga, R. Caputto
doaj +1 more source