Involvement of glycogen debranching enzyme in bladder cancer. [PDF]
Biomed Rep, 2017 Bladder cancer is the most common malignancy of the urinary system, however the molecular pathways underlying this disease are incompletely understood. To understand new regulators of bladder cancer progression, the authors carried out a functional genomic screen which identified glycogen debranching enzyme (AGL) as a novel regulator of bladder cancer ...
Weinhaus B, Guin S.
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Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase. [PDF]
Mol Neurobiol, 2014 In Lafora disease (LD), the deficiency of either EPM2A or NHLRC1, the genes encoding the phosphatase laforin and E3 ligase, respectively, causes massive accumulation of less-branched glycogen inclusions, known as Lafora bodies, also called polyglucosan bodies (PBs), in several types of cells including neurons.
Liu Y +6 more
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The Saccharomyces cerevisiae YPR184w gene encodes the glycogen debranching enzyme [PDF]
FEMS Microbiology Letters, 2000 The YPR184w gene encodes a 1536-amino acid protein that is 34-39% identical to the mammal, Drosophila melanogaster and Caenorhabditis elegans glycogen debranching enzyme. The N-terminal part of the protein possesses the four conserved sequences of the alpha-amylase superfamily, while the C-terminal part displays 50% similarity with the C-terminal of ...
Marie-Ange Teste
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Identification of isoamylase, a glycogen‐debranching enzyme, from Bacillus amyloliquefaciens [PDF]
FEBS Letters, 1975 Bacillus arnyloliquefaciens is well known for its production of an extracellular cu-amylase. The enzyme is secreted into the culture fluid during the exponential phase of growth when the bacteria are grown with an amylaceous carbon source, e.g. maltose, maltodextrins, soluble starch, or glycogen.
Herbert Urlaub, Günter Wöber
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LEUKOCYTE DEBRANCHING ENZYME IN GLYCOGEN STORAGE DISEASE [PDF]
Journal of Clinical Investigation, 1963 Hibbard E. Williams +2 more
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Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth. [PDF]
Oncotarget, 2018 Richmond CS +6 more
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Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis. [PDF]
Clin Cancer Res, 2016 Guin S +6 more
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The significance of the activity of glycogen debranching enzyme in glycolysis in porcine and bovine muscles [PDF]
Meat Science, 2005 The purpose of the study was to examine the activity of glycogen debranching enzyme, GDE, in porcine and bovine muscles differing in rate of contraction and oxidative capacity. The activity of GDE, the activity of phosphorylase, total glucose content, lactate content and pH were measured from meat samples taken 35min post-mortem and ultimate pH 24 or ...
Maria Ylä‐Ajos +2 more
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Structural insight into the bifunctional mechanism of the glycogen-debranching enzyme TreX from the archaeon Sulfolobus solfataricus. [PDF]
J Biol Chem, 2008 Woo EJ +6 more
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Mono-(2-ethylhexyl) phthalate Targets Glycogen Debranching Enzyme and Affects Glycogen Metabolism in Rat Testis [PDF]
Toxicological Sciences, 2009 Phthalate esters are commonly used plasticizers; however, some are suspected to cause reproductive toxicity. Administration of high doses of di-(2-ethylhexyl) phthalate (DEHP) induces germ cell death in male rodents. Mono-(2-ethylhexyl) phthalate (MEHP), a hydrolyzed metabolite of DEHP, appears to be responsible for this testicular toxicity; however ...
Chikanori Kuramori +13 more
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